TWO SIGMA INVESTMENTS, LP
Institutional investor · Portfolio as of Q3 2025
Top Holdings3,628 positions
STATE STR SPDR S&P 500 ETF T | 1M | $680.4M | 1.0% | $508.28 | +29.67% | 28 qtrssince 2018-Q4 | Decreased 0 |
SELECT SECTOR SPDR TR | 10.8M | $582.6M | 0.9% | $52.67 | +0.68% | 3 qtrssince 2025-Q1 | Increased 72 |
SELECT SECTOR SPDR TR | 6.2M | $489.6M | 0.7% | $76.86 | -0.76% | 2 qtrssince 2025-Q2 | Increased 71 |
VANGUARD | 866,100 | $415.4M | 0.6% | $59.66 | +33.42% | 10 qtrssince 2023-Q2 | Decreased 0 |
INVESCO QQQ TR | 673,858 | $404.6M | 0.6% | $443.66 | +34.78% | 27 qtrssince 2019-Q1 | Decreased 0 |
ISHARES TR | 1.9M | $375.7M | 0.6% | $176.72 | +9.06% | 10 qtrssince 2023-Q2 | Increased 71 |
ISHARES TR | 500,700 | $335.1M | 0.5% | $514.28 | +28.62% | 10 qtrssince 2023-Q2 | Decreased 0 |
PALANTIR TECHNOLOGIES INC | 1.6M | $290.1M | 0.4% | $85.22 | +109.88% | 14 qtrssince 2022-Q2 | Decreased 0 |
MICRON TECHNOLOGY INC | 1.7M | $285.3M | 0.4% | $152.82 | +9.32% | 11 qtrssince 2023-Q1 | Increased 60 |
ISHARES TR | 586,857 | $274.9M | 0.4% | $85.04 | +37.20% | 10 qtrssince 2023-Q2 | Decreased 0 |
LOCKHEED MARTIN CORP | 549,482 | $274.3M | 0.4% | $420.89 | +15.62% | 28 qtrssince 2018-Q4 | Increased 45 |
ALNYLAM PHARMACEUTICALS INC | 595,926 | $271.7M | 0.4% | $353.60 | +28.96% | 7 qtrssince 2024-Q1 | Increased 55 |
NEBIUS GROUP N.V. | 2.4M | $270.5M | 0.4% | $108.45 | +1.63% | 2 qtrssince 2025-Q2 | Increased 59 |
NVIDIA CORPORATION | 1.4M | $270.2M | 0.4% | $77.26 | +140.92% | 11 qtrssince 2023-Q1 | Decreased 0 |
MICROSOFT CORP | 515,209 | $266.9M | 0.4% | $349.84 | +46.84% | 10 qtrssince 2023-Q2 | Decreased 0 |
AMAZON COM INC | 1.2M | $266.4M | 0.4% | $218.81 | +0.35% | 17 qtrssince 2021-Q3 | Decreased 0 |
CLOUDFLARE INC | 1.2M | $265.4M | 0.4% | $103.61 | +110.97% | 16 qtrssince 2021-Q4 | Decreased 0 |
REGENERON PHARMACEUTICALS | 469,903 | $264.2M | 0.4% | $621.94 | -10.06% | 5 qtrssince 2024-Q3 | Decreased 0 |
ISHARES TR | 2.7M | $260.1M | 0.4% | $92.37 | +1.51% | 3 qtrssince 2025-Q1 | Increased 45 |
BANK OF AMER CORP | 5M | $255.8M | 0.4% | $43.53 | +16.05% | 5 qtrssince 2024-Q3 | Decreased 0 |
TWO SIGMA INVESTMENTS, LP manages $67.2B across 3628 positions as of Q3 2025. Top holdings: SPY (1.0%), XLF (0.9%), XLP (0.7%). Fund DNA: Diversified Scout. HoldingsIntel Score: 2.5/5.0.
Active quarter - 681 new positions, 433 exits, 1458 increased. Top move: XLF (INCREASED, conviction 72). Portfolio: $67.2B across 3628 positions.
Top holdings by portfolio weight
Portfolio allocation by GICS sector
Behavioral investing profile
Position Outcomes
Best and worst performing positions by estimated return
Top Winners
Top Losers
Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer
Verify source filings on SEC EDGAR