Back to RTW INVESTMENTS, LP RTW INVESTMENTS, LP

SYRESYRE
11 quarters

Position history for RTW INVESTMENTS, LPRTW INVESTMENTS, LP's holdings in SPYRE THERAPEUTICS INC

Yes. RTW Investments holds 4,251,996 shares of SYRE (Spyre Therapeutics), worth $377.5M, as of its Q2 2026 13F filing. It increased the position by 80,000 shares (+1.9%) from Q1 2026. RTW Investments has held SYRE since Q4 2023, across 11 quarterly 13F filings. SYRE is 3.2% of RTW Investments' reported 13F portfolio.

Current Value

$377.5M

Current Shares

4.3M

Total Value Change

+$329.4M

Total Shares Change

+2M

Quarter-by-Quarter History
QuarterActionSharesChangeValueWeightPriceConviction
2026-Q2
Latest
Increased
4.3M
+1.9%
$377.5M3.2%$88.78
58
2026-Q1
Unchanged
4.2M
0.0%
$210.4M2.1%$50.44
0
2025-Q4
Increased
4.2M
+15.2%
$136.7M1.4%$32.76
55
2025-Q3
Unchanged
3.6M
0.0%
$60.7M0.7%$16.76
0
2025-Q2
Unchanged
3.6M
0.0%
$54.2M0.8%$14.97
0
2025-Q1
Unchanged
3.6M
0.0%
$58.4M0.9%$16.14
0
2024-Q4
Increased
3.6M
+11.2%
$84.3M1.3%$23.28
52
2024-Q3
Unchanged
3.3M
0.0%
$95.8M1.4%$29.41
0
2024-Q2
Increased
3.3M
+45.9%
$76.6M1.2%$23.51
64
2024-Q1
Unchanged
2.2M
0.0%
$84.7M1.3%$37.93
0
2023-Q4
New
2.2M
-
$48M0.8%$21.52
57

Other major holders of SYRE: FMR LLC, BlackRock, Inc., VANGUARD CAPITAL MANAGEMENT LLC

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