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SYRESYRE
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Position history for FMR LLCFMR LLC's holdings in SPYRE THERAPEUTICS INC

FMR LLC holds 13M shares of SYRE (SPYRE THERAPEUTICS INC), worth $1.2B as of 2026-Q2. The position was increased (+10.6% shares). SYRE represents 0.1% of FMR LLC's portfolio.

Current Value

$1.2B

Current Shares

13M

Total Value Change

+$932.2M

Total Shares Change

+5.4M

Quarter-by-Quarter History
QuarterActionSharesChangeValueWeightPriceConviction
2026-Q2
Latest
Increased
13M
+10.6%
$1.2B0.1%$88.78
35
2026-Q1
Increased
11.8M
+1.2%
$594.2M0.0%$50.44
32
2025-Q4
Increased
11.6M
+28.5%
$381.3M0.0%$32.76
39
2025-Q3
Increased
9.1M
+0.1%
$151.8M0.0%$16.76
30
2025-Q2
Increased
9.1M
+0.2%
$135.5M0.0%$14.97
30
2025-Q1
Increased
9M
+2.7%
$145.8M0.0%$16.14
31
2024-Q4
Increased
8.8M
+15.4%
$204.9M0.0%$23.28
35
2024-Q3
Increased
7.6M
+1.5%
$224.2M0.0%$29.41
31

Other major holders of SYRE: BlackRock, Inc., RTW INVESTMENTS, LP, VANGUARD CAPITAL MANAGEMENT LLC, STATE STREET CORP

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