Duquesne Family Office LLC
Institutional investor · Portfolio as of Q4 2025
Top Holdings62 positions
Stock | Shares | Value | Weight | Avg Buy | Est. P&L | Held | Conviction |
|---|---|---|---|---|---|---|---|
NATERA INC | 2.5M | $575.3M | 12.8% | $98.33 | +133.90% | 14 qtrssince 2022-Q3 | Decreased 0 |
FINANCIAL SELECT SECTOR SPDR | 5.5M | $301M | 6.7% | $55.18 | +5.40% | 1 qtr | New 95 |
INSMED INC | 1.5M | $257.9M | 5.7% | $88.05 | +97.71% | 7 qtrssince 2024-Q2 | Decreased 0 |
INVESCO S&P 500 EQUAL WEIGHT | 1.2M | $224.9M | 5.0% | $193.21 | +15.30% | 1 qtr | New 95 |
TEVA PHARMACEUTICAL-SP ADR | 5.9M | $183.4M | 4.1% | $18.85 | +66.24% | 6 qtrssince 2024-Q3 | Decreased 0 |
WOODWARD INC | 590,930 | $178.7M | 4.0% | $150.13 | +101.90% | 9 qtrssince 2023-Q4 | Decreased 0 |
AMAZON.COM INC | 737,940 | $170.3M | 3.8% | $226.39 | +2.71% | 2 qtrssince 2025-Q3 | Increased 83 |
TAIWAN SEMICONDUCTOR SPONSORED ADR /1 ADR REPS 5 ORD SHS/ | 543,085 | $165M | 3.7% | $180.59 | +65.89% | 6 qtrssince 2024-Q3 | Decreased 0 |
COUPANG INC | 6.8M | $159.8M | 3.6% | $30.83 | -21.72% | 20 qtrssince 2021-Q1 | Increased 76 |
ISHARES MSCI BRAZIL ETF | 4.2M | $134.3M | 3.0% | — | — | — | New — |
ALPHABET INC-CL A | 385,000 | $120.5M | 2.7% | $295.28 | +17.14% | 2 qtrssince 2025-Q3 | Increased 83 |
SEA LTD-ADR | 944,120 | $120.4M | 2.7% | $137.34 | -6.55% | 3 qtrssince 2025-Q2 | Increased 83 |
ISHARES MSCI BRAZIL ETF | 3.6M | $112.9M | 2.5% | $31.99 | 0.00% | 1 qtr | New 78 |
NewAmsterdam Pharma Company N.V. | 3.1M | $107.7M | 2.4% | $28.10 | +23.61% | 6 qtrssince 2024-Q3 | Increased 74 |
MERCADOLIBRE INC | 47,149 | $95M | 2.1% | $1,802.75 | +12.10% | 7 qtrssince 2024-Q2 | Decreased 0 |
BBB FOODS INC | 2.7M | $89.3M | 2.0% | $30.60 | +9.34% | 3 qtrssince 2025-Q2 | Increased 76 |
RESTAURANT BRANDS INTERN | 1.2M | $82.5M | 1.8% | $64.72 | +6.23% | 3 qtrssince 2025-Q2 | Increased 50 |
Cogent Biosciences, Inc. | 2.2M | $78.7M | 1.8% | $26.12 | +45.22% | 2 qtrssince 2025-Q3 | Increased 76 |
ALCOA CORP | 1.4M | $73.1M | 1.6% | $52.87 | 0.00% | 1 qtr | New 68 |
ENTEGRIS INC | 844,160 | $71.1M | 1.6% | $84.05 | +92.46% | 1 qtr | New 68 |
Duquesne Family Office LLC manages $4.5B across 62 positions as of Q4 2025. Top holdings: NTRA (12.8%), XLF (6.7%), INSM (5.7%). Fund DNA: Momentum Trader. HoldingsIntel Rating: 2.5/5.0.
Active quarter - 26 new positions, 30 exits, 13 increased. Top move: XLF (NEW, conviction 95). Portfolio: $4.5B across 62 positions.
Top holdings by portfolio weight
Portfolio allocation by GICS sector
Behavioral investing profile
Position Outcomes
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Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer