TYRA BIOSCIENCES INC (TYRA) is held by 99 institutional investors that disclose positions via SEC 13F filings. The largest disclosed holder is RA CAPITAL MANAGEMENT, L.P. as of Q1 2026.

Are institutions buying or selling TYRA?

In Q1 2026, 67 institutions opened or increased positions in TYRA BIOSCIENCES INC while 25 reduced or exited — a net buying quarter.

What is the Smart Money Verdict on TYRA?

The Smart Money Verdict combines four independent sources (institutional 13F activity, insider trades, activist filings, and congressional trades) into a single assessment for TYRA BIOSCIENCES INC.

How many hedge funds hold TYRA?

99 institutional investors report holding TYRA BIOSCIENCES INC (TYRA) as of Q1 2026, based on SEC 13F filings.

Is institutional money flowing into TYRA?

As of Q1 2026, tracked institutions in TYRA BIOSCIENCES INC show 67 buyers versus 25 sellers — net inflows.

TYRA BIOSCIENCES INC

TYRA·90240B106·US·Common Stock·Healthcare - Biotechnology-Activist

Holders

(7 Elite)

$1.6B

Total Value

73% (92)

Consensus

67 buying - 25 selling

13F: Mar 31, 2026Insider & Congress: Updated regularly

Smart Money Verdict

View all

Held by 99 funds

7 elite

Who's Trading

ActivistCOCommodore Capital LP4.2%May 15, 2026

Activist

JANUS HENDERSON GROUP PLC7.2%May 15, 2026

ActivistTHTodd Harris4.8%May 14, 2026

ActivistDJDapice Joshua J.6.6%May 12, 2026

InsiderHTHarris ToddVest 79K shMay 5, 2026

InsiderRYRueb YuliyaVest 8K shMay 5, 2026

InsiderFAFuhrman AlanVest 20K shMay 5, 2026

InsiderWJWarner Douglas JVest 25K shMay 5, 2026

InsiderABAshar BhaveshVest 15K shMay 5, 2026

ActivistCXCanaan XI L.P.1.4%Apr 24, 2026

View all insider trades View all activist filings

Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
RA CAPITAL MANAGEMENT, L.P.	Unchanged	12.2M	$467.2M	5.0%	+108.29%	0
FMR LLC	Increased	7.7M(+616x)	$296.7M	0.0%	-0.69%	50
Janus Henderson Group Ltd.	Increased	3.9M(+32.5%)	$148.9M	0.1%	+62.52%	39
FARALLON CAPITAL MANAGEMENT, L.L.C.	Increased	3.6M(+73.3%)	$137.1M	0.8%	+32.11%	64
BlackRock, Inc.	Increased	2.2M(+6.3%)	$84.9M	0.0%	+108.07%	32
STATE STREET CORP	Increased	1.2M(+62.3%)	$46.6M	0.0%	+33.49%	42
VAVANGUARD CAPITAL MANAGEMENT LLC	New	1.1M	$43.1M	0.0%	-0.79%	40
PRICE T ROWE ASSOCIATES INC /MD/	Increased	986,061(+6732.5%)	$37.8M	0.0%	+0.18%	47
BARCLAYS PLC	Increased	833,399(+992.1%)	$31.9M	0.0%	+3.35%	47
GEODE CAPITAL MANAGEMENT, LLC	Increased	658,482(+0.1%)	$25.2M	0.0%	+118.95%	29
JENNISON ASSOCIATES LLC	New	632,432	$24.2M	0.0%	-0.79%	40
GOLDMAN SACHS GROUP INC	Increased	550,334(+201.7%)	$21.1M	0.0%	+16.66%	46
BALYASNY ASSET MANAGEMENT L.P.	Decreased	351,479(-57.0%)	$13.5M	0.0%	+209.01%	0
Woodline Partners LP	New	301,040	$11.5M	0.0%	-0.79%	39
VPVANGUARD PORTFOLIO MANAGEMENT LLC	New	247,270	$9.5M	0.0%	-0.79%	38
RAYMOND JAMES FINANCIAL INC	Increased	247,098(+45.3%)	$9.5M	0.0%	+51.80%	38
MILLENNIUM MANAGEMENT LLC	Increased	221,581(+93.7%)	$8.5M	0.0%	+43.74%	44
NORTHERN TRUST CORP	Increased	218,508(+8.7%)	$8.4M	0.0%	+82.31%	30
BANK OF AMERICA CORP /DE/	Increased	209,922(+448.0%)	$8M	0.0%	+13.69%	44
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	Decreased	199,111(-0.2%)	$7.6M	0.0%	+135.14%	0