TYRA BIOSCIENCES INC

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TYRA·90240B106·US·Common Stock·Healthcare - Biotechnology-Activist

TYRA (TYRA BIOSCIENCES INC) is held by 100 institutional investors as of Q2 2026. Largest holders: RA CAPITAL MANAGEMENT, L.P. ($389.6M), FMR LLC ($284.9M), Jupiter Topco LLC ($139.2M). Net institutional sentiment: Bullish.

100

Holders

(7 Elite)

$1.5B

Total Value

67% (107)

Consensus

72 buying - 35 selling

13F: Jun 30, 2026Insider & Congress: Updated regularly

Smart Money Verdict

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Institutional (13F)85

Insider (Form 4)82

Activist (13D/13G)28

Congressional (STOCK Act)42

Holder Quality

85

★★★★★

Elite

89

★★★★

Strong

13

★★★

Solid

51

★★

Below

74

★

Weak

Held by 100 funds

7 elite

Who's Trading

Source dates: Price Oct 14, 2026 · Insiders Sep 17, 2026 · Activists Sep 21, 2026 · Congress none

ActivistBLBVF PARTNERS L P/IL6.1%Sep 21, 2026

ActivistPBParadigm BioCapital Advisors LP5.8%Sep 17, 2026

ActivistRA Capital Management, L.P.19.9%Sep 17, 2026

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Top Holders

Top Holders (100)History

AllNewIncreasedHeldDecreasedExitedFirst report

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Fund	Action	Shares	Value	Weight	Est. P&L	Conviction
RA CAPITAL MANAGEMENT, L.P.	Unchanged	12.2M	$389.6M	3.4%	+18.04%	0
FMR LLC	Increased	8.9M(+15.1%)	$284.9M	0.0%	-51.49%	35
JTJupiter Topco LLC	First report	4.4M	$139.2M	0.1%	-41.89%	0
BlackRock, Inc.	Increased	3M(+36.7%)	$96.8M	0.0%	+21.33%	39
PRICE T ROWE ASSOCIATES INC /MD/	Increased	2.8M(+182.2%)	$88.9M	0.0%	-34.70%	48
STATE STREET CORP	Increased	2.1M(+76.0%)	$68.4M	0.0%	-32.34%	45
VAVANGUARD CAPITAL MANAGEMENT LLC	Increased	1.5M(+34.0%)	$48.2M	0.0%	-27.31%	38
Hood River Capital Management LLC	New	1M	$32.5M	0.2%	-41.89%	48
GEODE CAPITAL MANAGEMENT, LLC	Increased	970,734(+47.4%)	$31M	0.0%	+24.15%	39
MWMARSHALL WACE, LLP	Increased	583,133(+194.9%)	$18.6M	0.0%	-17.88%	46
GOLDMAN SACHS GROUP INC	Decreased	463,477(-15.8%)	$14.8M	0.0%	-41.97%	0
JENNISON ASSOCIATES LLC	Decreased	450,964(-28.7%)	$14.4M	0.0%	-27.31%	0
TWO SIGMA INVESTMENTS, LP	Increased	449,808(+342.6%)	$14.4M	0.0%	-27.16%	45
VPVANGUARD PORTFOLIO MANAGEMENT LLC	Increased	403,019(+63.0%)	$12.9M	0.0%	-28.74%	41
BANK OF AMERICA CORP /DE/	Increased	349,732(+66.6%)	$11.2M	0.0%	-43.88%	41
Walleye Capital LLC	Increased	347,898(+1758.9%)	$11.1M	0.0%	-40.93%	45
Woodline Partners LP	Increased	320,040(+6.3%)	$10.2M	0.0%	-27.31%	30
NORTHERN TRUST CORP	Increased	310,084(+41.9%)	$9.9M	0.0%	+6.89%	37
MORGAN STANLEY	Increased	300,322(+149.3%)	$9.6M	0.0%	-3.70%	45
CITADEL ADVISORS LLC	Increased	278,307(+1707.7%)	$8.9M	0.0%	-40.91%	44

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High Conviction Moves-Smart Money Convergence-Fund Consensus-Double-Down Detection

Data sourced from four public-disclosure sources: SEC 13F, Form 4, 13D/13G, and House/Senate STOCK Act disclosures. Not financial advice. Full disclaimer