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SYRESYRE
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Position history for STATE STREET CORPSTATE STREET CORP's holdings in Spyre Therapeutics, Inc

STATE STREET CORP holds 3.1M shares of SYRE (Spyre Therapeutics, Inc), worth $271.4M as of 2026-Q2. The position was increased (+17.3% shares). SYRE represents 0.0% of STATE STREET CORP's portfolio.

Current Value

$271.4M

Current Shares

3.1M

Total Value Change

+$226.1M

Total Shares Change

+1.5M

Quarter-by-Quarter History
QuarterActionSharesChangeValueWeightPriceConviction
2026-Q2
Latest
Increased
3.1M
+17.3%
$271.4M0.0%$88.78
36
2026-Q1
Increased
2.6M
+15.2%
$131.5M0.0%$40.07
35
2025-Q4
Increased
2.3M
+26.8%
$74.1M0.0%$31.88
37
2025-Q3
Increased
1.8M
+11.9%
$29.9M0.0%$16.36
32
2025-Q2
Decreased
1.6M
-6.0%
$23.9M0.0%$15.22
0
2025-Q1
Increased
1.7M
+1.0%
$27.4M0.0%$17.94
29
2024-Q4
Increased
1.7M
+9.0%
$39.1M0.0%$22.54
32
2024-Q3
Increased
1.5M
+9.4%
$45.3M0.0%$28.49
32

Other major holders of SYRE: FMR LLC, BlackRock, Inc., RTW INVESTMENTS, LP

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