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SYRE
4 quarters

Position history for BAKER BROS. ADVISORS LP's holdings in SPYRE THERAPEUTICS INC

BAKER BROS. ADVISORS LP holds 1M shares of SYRE (SPYRE THERAPEUTICS INC), worth $50.4M as of 2026-Q1. SYRE represents 0.3% of BAKER BROS. ADVISORS LP's portfolio.

Current Value

$50.4M

Current Shares

1M

Total Value Change

+$41.1M

Total Shares Change

+373,297

Quarter-by-Quarter History
QuarterActionSharesChangeValueWeightPriceConviction
2026-Q1
Latest
Unchanged
1M
0.0%
$50.4M0.3%$40.07
0
2025-Q4
Unchanged
1M
0.0%
$32.8M0.2%$31.88
0
2025-Q3
Increased
1M
+59.6%
$16.8M0.1%$16.36
48
2025-Q2
New
626,703
-
$9.4M0.1%$15.22
38

Other major holders of SYRE: FMR LLC, BlackRock, Inc., RTW INVESTMENTS, LP

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