RA CAPITAL MANAGEMENT, L.P.RA CAPITAL MANAGEMENT, L.P.

Institutional investor · Portfolio as of Q1 2023

Top Holdings59 positions

Checking export access…
Activity:
ASNDASND
ADR

ASCENDIS PHARMA A/S

7M$745.9M16.9%$95.96+13.13%
18 qtrssince 2018-Q4
Unchanged
0

VAXCYTE INC

7.3M$273.3M6.2%$34.23+5.95%
12 qtrssince 2020-Q2
Increased
73
DICEDICEDelisted

DICE THERAPEUTICS INC

7.9M$225.1M5.1%——
7 qtrssince 2021-Q3
Increased
68
ETNBETNBDelisted

89BIO INC

11.4M$173.9M3.9%——
14 qtrssince 2019-Q4
Increased
69
8.3M$166.7M3.8%——
8 qtrssince 2021-Q2
Unchanged
0

BIOGEN INC

532,892$148.2M3.4%$222.99+23.38%
5 qtrssince 2022-Q1
Unchanged
0
VRNAVRNADelisted
ADR

VERONA PHARMA PLC

6.3M$126.9M2.9%——
11 qtrssince 2020-Q3
Unchanged
0

CYTEK BIOSCIENCES INC

13.4M$123M2.8%$18.15-50.90%
7 qtrssince 2021-Q3
Unchanged
0

VOR BIOPHARMA INC

22.7M$122.4M2.8%$449.88-76.70%
9 qtrssince 2021-Q1
Unchanged
0
LEGNLEGN
ADR

LEGEND BIOTECH CORP

2.4M$117.5M2.7%$40.50+18.51%
3 qtrssince 2022-Q3
Unchanged
0

TYRA BIOSCIENCES INC

7.2M$116.3M2.6%$16.91-7.16%
7 qtrssince 2021-Q3
Unchanged
0

JANUX THERAPEUTICS INC

8.7M$104.9M2.4%$25.37-54.28%
8 qtrssince 2021-Q2
Unchanged
0

PEPGEN INC

8.1M$99.5M2.3%$9.93+23.16%
4 qtrssince 2022-Q2
Unchanged
0
RNAMRNAMDelisted

AVIDITY BIOSCIENCES INC

6.4M$98.5M2.2%$20.32-17.32%
7 qtrssince 2021-Q3
Increased
60

RHYTHM PHARMACEUTICALS INC

5.5M$98.4M2.2%$23.70-24.74%
18 qtrssince 2018-Q4
Unchanged
0
DAWNDAWNDelisted

DAY ONE BIOPHARMACEUTICALS I

7M$94.1M2.1%$19.64-35.07%
8 qtrssince 2021-Q2
Unchanged
0
BLUBLUDelisted

BELLUS HEALTH INC NEW

12.6M$91M2.1%——
6 qtrssince 2021-Q4
Increased
52
CVACCVACDelisted

CUREVAC N V

12.2M$85.4M1.9%$6.670.00%
1 qtr
New
68

IMMUNOGEN INC

21.9M$83.9M1.9%——
11 qtrssince 2020-Q3
Unchanged
0

WAVE LIFE SCIENCES LTD

17.2M$74.5M1.7%$20.65-80.00%
18 qtrssince 2018-Q4
Unchanged
0
$4.4B
AUM
59
Positions
Q1 2023
Filing
HI score · 2.0/5
Quarterly 13F Value Change
-21%Q4'21$5.7B-19%Q1'22$4.6B-18%Q2'22$3.8B+25%Q3'22$4.7B+5%Q4'22$4.9B-10%Q1'23$4.4B
Activity profile
$ moved · Q1'23
New30%Increased33%Decreased8%Exited29%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 1.7 years
<1Q7%1-4Q19%1-2Y34%2Y+41%

RA CAPITAL MANAGEMENT, L.P. manages $4.4B across 59 positions as of Q1 2023. Top holdings: ASND (16.9%), PCVX (6.2%), DICE (5.1%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 2/5.0.

Q1 2023 Summary

Active quarter - 4 new positions, 15 exits, 12 increased. Top move: PCVX (INCREASED, conviction 73). Portfolio: $4.4B across 59 positions.

Top holdings by portfolio weight

Total AUM$4B
ASND16.89%
PCVX6.19%
DICE5.10%
ETNB3.94%
AEROVATE THE3.77%
BIIB3.35%
VRNA2.87%
CTKB2.78%
VOR2.77%
LEGN2.66%
Other2.63%

Portfolio allocation by GICS sector

Sectors2
Healthcare78.39%
Unknown21.61%

Behavioral investing profile

Checking access…
Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Below Average(2.0 / 5.0)
Holdings P&L22
Conviction41
Concentration91
Checking access…

Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
2Q
SLDBSLDBSOLID BIOSCIENCES INC
Q1 2026 → Q2 2026+6.2M shares+$87.5M
Checking access…

Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

Analytics tracking helps us improve the product. Essential functions stay on either way. How analytics data is used