RA CAPITAL MANAGEMENT, L.P.RA CAPITAL MANAGEMENT, L.P.

Institutional investor · Portfolio as of Q3 2023

Top Holdings66 positions

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Activity:
ASNDASND
ADR

ASCENDIS PHARMA A/S

10.7M$1B19.8%$92.74+0.97%
20 qtrssince 2018-Q4
Decreased
0
LEGNLEGN
ADR

LEGEND BIOTECH CORP

6.3M$420.8M8.3%$58.65+14.52%
5 qtrssince 2022-Q3
Unchanged
0

VAXCYTE INC

7.9M$402.3M7.9%$35.32+44.34%
14 qtrssince 2020-Q2
Unchanged
0

IMMUNOGEN INC

13.3M$211.4M4.2%——
13 qtrssince 2020-Q3
Increased
91
ETNBETNBDelisted

89BIO INC

11.4M$176.3M3.5%——
16 qtrssince 2019-Q4
Unchanged
0

Biogen Inc

532,892$137M2.7%$222.99+15.26%
7 qtrssince 2022-Q1
Unchanged
0

RHYTHM PHARMACEUTICALS INC

5.7M$130.1M2.6%$23.50-2.45%
20 qtrssince 2018-Q4
Unchanged
0
8.3M$112.1M2.2%——
10 qtrssince 2021-Q2
Unchanged
0
CBAYCBAYDelisted

CYMABAY THERAPEUTICS INC

6.9M$103.5M2.0%——
1 qtr
New
78
VRNAVRNADelisted
ADR

VERONA PHARMA PLC

6.3M$103M2.0%——
13 qtrssince 2020-Q3
Unchanged
0

TYRA BIOSCIENCES INC

7.2M$99.6M2.0%$16.91-18.57%
9 qtrssince 2021-Q3
Unchanged
0

WAVE LIFE SCIENCES LTD

17.2M$98.9M1.9%$20.65-72.16%
20 qtrssince 2018-Q4
Unchanged
0

GERON CORP

46.2M$97.9M1.9%$2.16-1.71%
14 qtrssince 2020-Q2
Increased
64
DAWNDAWNDelisted

DAY ONE BIOPHARMACEUTICALS I

7.8M$95.8M1.9%$18.91-35.12%
10 qtrssince 2021-Q2
Unchanged
0

JANUX THERAPEUTICS INC

9.2M$92.4M1.8%$24.54-58.93%
10 qtrssince 2021-Q2
Increased
50

AN2 THERAPEUTICS INC

5.6M$89.3M1.8%$15.24+5.49%
7 qtrssince 2022-Q1
Increased
64

INHIBRX INC

4.7M$86.7M1.7%——
4 qtrssince 2022-Q4
Increased
57

RXSIGHT INC

3.1M$85.1M1.7%$12.40+124.92%
9 qtrssince 2021-Q3
Unchanged
0

NEWAMSTERDAM PHARMA CO NV

9M$83.3M1.6%$11.45-19.21%
4 qtrssince 2022-Q4
Unchanged
0

EVOLENT HEALTH INC

2.7M$74.5M1.5%$27.230.00%
1 qtr
New
68
$5.1B
AUM
66
Positions
Q3 2023
Filing
HI score · 2.0/5
Quarterly 13F Value Change
-18%Q2'22$3.8B+25%Q3'22$4.7B+5%Q4'22$4.9B-10%Q1'23$4.4B+20%Q2'23$5.3B-4%Q3'23$5.1B
Activity profile
$ moved · Q3'23
New34%Increased25%Decreased10%Exited31%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 1.8 years
<1Q17%1-4Q17%1-2Y12%2Y+55%

RA CAPITAL MANAGEMENT, L.P. manages $5.1B across 66 positions as of Q3 2023. Top holdings: ASND (19.8%), LEGN (8.3%), PCVX (7.9%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 2/5.0.

Q3 2023 Summary

Active quarter - 14 new positions, 2 exits, 10 increased. Top move: IMGN (INCREASED, conviction 91). Portfolio: $5.1B across 66 positions.

Top holdings by portfolio weight

Total AUM$5B
ASND19.76%
LEGN8.28%
PCVX7.92%
IMGN4.16%
ETNB3.47%
BIIB2.70%
RYTM2.56%
AEROVATE THE2.21%
CBAY2.04%
VRNA2.03%
Other1.96%

Portfolio allocation by GICS sector

Sectors2
Healthcare84.45%
Unknown15.55%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Below Average(2.0 / 5.0)
Holdings P&L21
Conviction41
Concentration91
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
2Q
SLDBSLDBSOLID BIOSCIENCES INC
Q1 2026 → Q2 2026+6.2M shares+$87.5M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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