DRIEHAUS CAPITAL MANAGEMENT LLC
Institutional investor · Portfolio as of Q4 2025
Top Holdings404 positions
Stock | Shares | Value | Weight | Avg Buy | Est. P&L | Held | Conviction |
|---|---|---|---|---|---|---|---|
TAIWAN SEMICONDUCTOR SPONSORED ADR /1 ADR REPS 5 ORD SHS/ | 2.2M | $657.5M | 4.5% | $64.83 | +362.12% | 28 qtrssince 2019-Q1 | Decreased 0 |
CRINETICS PHARMACEUTICALS IN | 6.4M | $297.3M | 2.0% | $26.60 | +78.13% | 23 qtrssince 2020-Q2 | Decreased 0 |
PRAXIS PRECISION MEDICINES I | 933,061 | $275M | 1.9% | $162.36 | +82.94% | 8 qtrssince 2024-Q1 | Increased 76 |
Guardant Health, Inc. | 2.1M | $218.9M | 1.5% | $44.83 | +124.39% | 4 qtrssince 2025-Q1 | Decreased 0 |
XENON PHARMACEUTICALS INC | 4.5M | $203.4M | 1.4% | $28.88 | +52.80% | 24 qtrssince 2020-Q1 | Increased 53 |
PLANET LABS PBC | 8.5M | $167.8M | 1.1% | $9.96 | +98.28% | 3 qtrssince 2025-Q2 | Decreased 0 |
APOGEE THERAPEUTICS INC | 2.2M | $164.8M | 1.1% | $41.31 | +83.41% | 10 qtrssince 2023-Q3 | Increased 48 |
EOS ENERGY ENTERPRISES INC | 14.3M | $163.5M | 1.1% | $8.05 | +41.03% | 4 qtrssince 2025-Q1 | Increased 77 |
SITIME CORP | 412,873 | $145.8M | 1.0% | $212.96 | +70.81% | 7 qtrssince 2024-Q2 | Decreased 0 |
NATERA INC | 625,912 | $143.4M | 1.0% | $88.34 | +160.35% | 14 qtrssince 2022-Q3 | Increased 46 |
CAMECO CORP | 1.5M | $139.3M | 0.9% | $49.70 | +83.84% | 18 qtrssince 2021-Q3 | Decreased 0 |
FTAI AVIATION LTD | 700,525 | $137.9M | 0.9% | $52.86 | +270.33% | 12 qtrssince 2023-Q1 | Increased 46 |
RHYTHM PHARMACEUTICALS INC | 1.3M | $137.6M | 0.9% | $46.42 | +129.99% | 14 qtrssince 2022-Q3 | Decreased 0 |
HDFC BANK LTD-ADR | 3.7M | $136M | 0.9% | $35.96 | -35.62% | 3 qtrssince 2025-Q2 | Increased 49 |
CREDICORP LTD | 472,044 | $135.5M | 0.9% | $170.02 | +70.57% | 8 qtrssince 2024-Q1 | Increased 46 |
Septerna, Inc. | 4.8M | $134.1M | 0.9% | $17.10 | +62.46% | 5 qtrssince 2024-Q4 | Decreased 0 |
NU HOLDINGS LTD/CAYMAN ISL-A | 7.7M | $129M | 0.9% | $15.30 | +10.36% | 3 qtrssince 2025-Q2 | Increased 67 |
BRIDGEBIO PHARMA INC | 1.7M | $128.6M | 0.9% | $36.00 | +112.47% | 4 qtrssince 2025-Q1 | Increased 43 |
Impinj, Inc. | 737,474 | $128.3M | 0.9% | $176.69 | -2.82% | 2 qtrssince 2025-Q3 | Increased 57 |
CARPENTER TECHNOLOGY | 403,296 | $127M | 0.9% | $217.13 | +46.65% | 6 qtrssince 2024-Q3 | Increased 58 |
DRIEHAUS CAPITAL MANAGEMENT LLC manages $14.7B across 404 positions as of Q4 2025. Top holdings: TSM (4.5%), CRNX (2.0%), PRAX (1.9%). Fund DNA: Momentum Trader. HoldingsIntel Rating: 2/5.0.
Active quarter - 89 new positions, 116 exits, 135 increased. Top move: EOSE (INCREASED, conviction 77). Portfolio: $14.7B across 404 positions.
Top holdings by portfolio weight
Portfolio allocation by GICS sector
Behavioral investing profile
Position Outcomes
Best and worst performing positions by estimated return
Top Winners
Top Losers
Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer