DRIEHAUS CAPITAL MANAGEMENT LLC
Institutional investor · Portfolio as of Q4 2025
Top Holdings404 positions
Taiwan Semiconductor Mfg Co Lt | 2.2M | $657.5M | 4.5% | $64.27 | +369.13% | 28 qtrssince 2019-Q1 | Decreased 0 |
CRINETICS PHARMACEUTICALS IN | 6.4M | $297.3M | 2.0% | $26.71 | +74.25% | 23 qtrssince 2020-Q2 | Decreased 0 |
PRAXIS PRECISION MEDICINES I | 933,061 | $275M | 1.9% | $161.00 | +83.06% | 8 qtrssince 2024-Q1 | Increased 76 |
Guardant Health, Inc. | 2.1M | $218.9M | 1.5% | $44.67 | +128.66% | 4 qtrssince 2025-Q1 | Decreased 0 |
XENON PHARMACEUTICALS INC | 4.5M | $203.4M | 1.4% | $28.88 | +52.80% | 24 qtrssince 2020-Q1 | Increased 53 |
PLANET LABS PBC | 8.5M | $167.8M | 1.1% | $9.96 | +98.28% | 3 qtrssince 2025-Q2 | Decreased 0 |
APOGEE THERAPEUTICS INC | 2.2M | $164.8M | 1.1% | $41.31 | +83.41% | 10 qtrssince 2023-Q3 | Increased 48 |
EOS ENERGY ENTERPRISES INC | 14.3M | $163.5M | 1.1% | $8.05 | +41.03% | 4 qtrssince 2025-Q1 | Increased 77 |
Sitime Corp | 412,873 | $145.8M | 1.0% | $212.96 | +70.81% | 7 qtrssince 2024-Q2 | Decreased 0 |
Natera Inc | 625,912 | $143.4M | 1.0% | $88.50 | +158.86% | 14 qtrssince 2022-Q3 | Increased 46 |
CAMECO CORP | 1.5M | $139.3M | 0.9% | $50.09 | +82.66% | 18 qtrssince 2021-Q3 | Decreased 0 |
Ftai Aviation Ltd | 700,525 | $137.9M | 0.9% | $52.86 | +270.33% | 12 qtrssince 2023-Q1 | Increased 46 |
RHYTHM PHARMACEUTICALS INC | 1.3M | $137.6M | 0.9% | $46.34 | +130.98% | 14 qtrssince 2022-Q3 | Decreased 0 |
HDFC BANK LTD | 3.7M | $136M | 0.9% | $37.34 | -33.36% | 3 qtrssince 2025-Q2 | Increased 49 |
Credicorp LTD | 472,044 | $135.5M | 0.9% | $159.72 | +71.58% | 8 qtrssince 2024-Q1 | Increased 46 |
SEPTERNA INC | 4.8M | $134.1M | 0.9% | $17.10 | +62.46% | 5 qtrssince 2024-Q4 | Decreased 0 |
Nu Holdings Ltd Cl A | 7.7M | $129M | 0.9% | $15.30 | +10.36% | 3 qtrssince 2025-Q2 | Increased 67 |
BRIDGEBIO PHARMA INC | 1.7M | $128.6M | 0.9% | $36.00 | +112.47% | 4 qtrssince 2025-Q1 | Increased 43 |
Impinj Inc | 737,474 | $128.3M | 0.9% | $176.69 | -0.75% | 2 qtrssince 2025-Q3 | Increased 57 |
Carpenter Technology Corp | 403,296 | $127M | 0.9% | $216.19 | +45.48% | 6 qtrssince 2024-Q3 | Increased 58 |
DRIEHAUS CAPITAL MANAGEMENT LLC manages $14.7B across 404 positions as of Q4 2025. Top holdings: TSM (4.5%), CRNX (2.0%), PRAX (1.9%). Fund DNA: Diversified Scout. HoldingsIntel Score: 1.5/5.0.
Active quarter - 89 new positions, 116 exits, 135 increased. Top move: EOSE (INCREASED, conviction 77). Portfolio: $14.7B across 404 positions.
Top holdings by portfolio weight
Portfolio allocation by GICS sector
Behavioral investing profile
Position Outcomes
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Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer
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