Avoro Capital Advisors LLCAvoro Capital Advisors LLC

Institutional investor · Portfolio as of Q1 2020

Top Holdings43 positions

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Activity:
IMMUIMMUDelisted

IMMUNOMEDICS INC

24.5M$330.3M11.1%——
5 qtrssince 2019-Q1
Unchanged
0
MRTXMRTXDelisted

MIRATI THERAPEUTICS INC

4.1M$316.1M10.7%——
5 qtrssince 2019-Q1
Increased
65

IOVANCE BIOTHERAPEUTICS INC COM

9M$269.7M9.1%$10.23+192.63%
5 qtrssince 2019-Q1
Increased
62
ASNDASND
ADR

ASCENDIS PHARMA A/S

1.8M$201.2M6.8%$117.47-1.25%
5 qtrssince 2019-Q1
Decreased
0

BIOMARIN PHARMACEUTICAL INC

1.9M$163.1M5.5%$84.82-2.75%
5 qtrssince 2019-Q1
Decreased
0

SAREPTA THERAPEUTICS INC

1.6M$155M5.2%$116.47-15.41%
5 qtrssince 2019-Q1
Decreased
0

HORIZON THERAPEUTICS PUB L

4.6M$135.5M4.6%——
4 qtrssince 2019-Q2
Increased
64

KARYOPHARM THERAPEUTICS INC

7M$134.5M4.5%———
Increased
66
ARGXARGX
ADR

ARGENX SE

936,500$123.4M4.2%$128.71+2.35%
5 qtrssince 2019-Q1
Unchanged
0
CNSTCNSTDelisted

CONSTELLATION PHARMCETICLS I

3.7M$114.7M3.9%——
2 qtrssince 2019-Q4
Unchanged
0
FOLDFOLDDelisted

AMICUS THERAPEUTICS INC

11M$101.2M3.4%$12.97-25.14%
5 qtrssince 2019-Q1
Decreased
0
DCPHDCPHDelisted

DECIPHERA PHARMACEUTICALS IN

2M$82.3M2.8%——
2 qtrssince 2019-Q4
Increased
83

UNIQURE NV

1.7M$78.3M2.6%$64.73-26.69%
3 qtrssince 2019-Q3
Decreased
0

ACCELERON PHARMA INC

860,000$77.3M2.6%——
1 qtr
New
78
ADVMADVMDelisted

ADVERUM BIOTECHNOLOGIES INC

7.2M$69.9M2.4%———
Increased
67
ZGNXZGNXDelisted

ZOGENIX INC

2.8M$69.2M2.3%——
5 qtrssince 2019-Q1
Increased
68
MYOKMYOKDelisted

MYOKARDIA INC

1.4M$67.3M2.3%——
5 qtrssince 2019-Q1
Decreased
0

PTC THERAPEUTICS INC

1.2M$53.5M1.8%$42.540.00%
1 qtr
New
68

RELMADA THERAPEUTICS INC COM

1.2M$39.2M1.3%$31.760.00%
1 qtr
New
67
ATNXATNXDelisted

ATHENEX INC

4.9M$37.7M1.3%——
4 qtrssince 2019-Q2
Decreased
0
$3B
AUM
43
Positions
Q1 2020
Filing
HI score · 2.5/5
Quarterly 13F Value Change
+25%Q2'19$2.9B-17%Q3'19$2.4B+42%Q4'19$3.4B-13%Q1'20$3B
Activity profile
$ moved · Q1'20
New32%Increased36%Decreased31%Exited1%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 2.3 quarters
<1Q28%1-4Q28%1-2Y44%2Y+0%

Avoro Capital Advisors LLC manages $3B across 43 positions as of Q1 2020. Top holdings: IMMU (11.1%), MRTX (10.7%), IOVA (9.1%). Fund DNA: Concentrated Value. HoldingsIntel Score: 2.5/5.0.

Q1 2020 Summary

Active quarter - 12 new positions, 0 exits, 9 increased. Top move: DCPH (INCREASED, conviction 83). Portfolio: $3.0B across 43 positions.

Top holdings by portfolio weight

Total AUM$3B
IMMU11.15%
MRTX10.67%
IOVA9.10%
ASND6.79%
BMRN5.50%
SRPT5.23%
HZNP4.57%
KPTI4.54%
ARGX4.16%
CNST3.87%
Other3.42%

Portfolio allocation by GICS sector

Sectors2
Healthcare50.87%
Unknown49.13%

Behavioral investing profile

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Concentrated Value- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(2.5 / 5.0)
Holdings P&L53
Conviction47
Concentration100
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
4Q
OCULOCULOCULAR THERAPEUTIX INC COM
Q3 2025 → Q2 2026+5.1M shares+$54.5M
3Q
UTHRUTHRUNITED THERAPEUTICS CORP DEL
Q4 2025 → Q2 2026+755,555 shares+$657.3M
2Q
ARWRARWRARROWHEAD PHARMACEUTICALS IN
Q1 2026 → Q2 2026+730,555 shares+$220.2M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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