Avoro Capital Advisors LLCAvoro Capital Advisors LLC

Institutional investor · Portfolio as of Q3 2020

Top Holdings46 positions

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Activity:
IMMUIMMUDelisted

IMMUNOMEDICS INC

26.3M$2.2B31.7%——
7 qtrssince 2019-Q1
Unchanged
0
MRTXMRTXDelisted

MIRATI THERAPEUTICS INC

4.3M$721.2M10.2%——
7 qtrssince 2019-Q1
Increased
63

HORIZON THERAPEUTICS PUB LTD

7.7M$594.3M8.4%——
6 qtrssince 2019-Q2
Increased
77

IOVANCE BIOTHERAPEUTICS INC

9.5M$313.9M4.5%$12.44+159.55%
7 qtrssince 2019-Q1
Decreased
0
ASNDASND
ADR

ASCENDIS PHARMA A S

1.8M$277.8M3.9%$118.44+28.55%
7 qtrssince 2019-Q1
Increased
59
MYOKMYOKDelisted

MYOKARDIA INC

1.9M$257M3.7%——
7 qtrssince 2019-Q1
Increased
57
ARGXARGX
ADR

ARGENX SE

902,500$236.9M3.4%$132.04+98.82%
7 qtrssince 2019-Q1
Decreased
0

SAREPTA THERAPEUTICS INC

1.7M$235.2M3.3%$118.96+18.77%
7 qtrssince 2019-Q1
Unchanged
0

ARENA PHARMACEUTICALS INC

3.1M$231.8M3.3%——
2 qtrssince 2020-Q2
Increased
92
FOLDFOLDDelisted

AMICUS THERAPEUTICS INC

10.9M$153.2M2.2%$12.98+8.46%
7 qtrssince 2019-Q1
Decreased
0

ACCELERON PHARMA INC

1.4M$151.9M2.2%——
3 qtrssince 2020-Q1
Increased
66

BIOMARIN PHARMACEUTICAL INC

1.8M$133.1M1.9%$84.82-10.40%
7 qtrssince 2019-Q1
Decreased
0
MRSNMRSNDelisted

MERSANA THERAPEUTICS INC

6.8M$126.6M1.8%$553.14-15.12%
2 qtrssince 2020-Q2
Increased
51

MADRIGAL PHARMACEUTICALS INC

890,000$105.7M1.5%$120.17-1.20%
7 qtrssince 2019-Q1
Increased
77
DCPHDCPHDelisted

DECIPHERA PHARMACEUTICALS IN

1.8M$93.4M1.3%——
4 qtrssince 2019-Q4
Decreased
0
ADAPYADAPYDelisted
ADR

ADAPTIMMUNE THERAPEUTICS PLC

11M$87.8M1.2%$9.14-16.21%
2 qtrssince 2020-Q2
Increased
53

KARYOPHARM THERAPEUTICS INC

6M$87.6M1.2%$171.34+33.94%
5 qtrssince 2019-Q3
Decreased
0
CNSTCNSTDelisted

CONSTELLATION PHARMCETICLS I

4.3M$86.6M1.2%——
4 qtrssince 2019-Q4
Increased
51
ADVMADVMDelisted

ADVERUM BIOTECHNOLOGIES INC

8M$82.4M1.2%$113.91-8.26%
6 qtrssince 2019-Q2
Increased
51
TRILTRILDelisted

TRILLIUM THERAPEUTICS INC

5.5M$78.2M1.1%——
3 qtrssince 2020-Q1
Increased
55
$7B
AUM
46
Positions
Q3 2020
Filing
HI score · 2.5/5
Quarterly 13F Value Change
+25%Q2'19$2.9B-17%Q3'19$2.4B+42%Q4'19$3.4B-13%Q1'20$3B+71%Q2'20$5.1B+39%Q3'20$7B
Activity profile
$ moved · Q3'20
New9%Increased67%Decreased17%Exited7%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 3.2 quarters
<1Q20%1-4Q37%1-2Y43%2Y+0%

Avoro Capital Advisors LLC manages $7B across 46 positions as of Q3 2020. Top holdings: IMMU (31.7%), MRTX (10.2%), HZNP (8.4%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 2.5/5.0.

Q3 2020 Summary

Active quarter - 9 new positions, 7 exits, 20 increased. Top move: ARNA (INCREASED, conviction 92). Portfolio: $7.0B across 46 positions.

Top holdings by portfolio weight

Total AUM$7B
IMMU31.71%
MRTX10.25%
HZNP8.44%
IOVA4.46%
ASND3.95%
MYOK3.65%
ARGX3.37%
SRPT3.34%
ARNA3.29%
FOLD2.18%
Other2.16%

Portfolio allocation by GICS sector

Sectors2
Unknown68.33%
Healthcare31.67%

Behavioral investing profile

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Balanced Allocator- primarily Unknown, Healthcare
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(2.5 / 5.0)
Holdings P&L53
Conviction47
Concentration100
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

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Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
4Q
OCULOCULOCULAR THERAPEUTIX INC
Q3 2025 → Q2 2026+5.1M shares+$54.5M
3Q
UTHRUTHRUnited Therapeutics Corp
Q4 2025 → Q2 2026+755,555 shares+$657.3M
2Q
ARWRARWRArrowhead Pharmaceuticals Inc
Q1 2026 → Q2 2026+730,555 shares+$220.2M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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