Avoro Capital Advisors LLCAvoro Capital Advisors LLC

Institutional investor · Portfolio as of Q3 2019

Top Holdings33 positions

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Activity:
MRTXMRTXDelisted

MIRATI THERAPEUTICS INC

3.8M$292.2M12.2%——
3 qtrssince 2019-Q1
Decreased
0
IMMUIMMUDelisted

IMMUNOMEDICS INC

21M$278.5M11.6%——
3 qtrssince 2019-Q1
Unchanged
0

IOVANCE BIOTHERAPEUTICS INC COM

10.6M$192.9M8.0%$9.82+83.21%
3 qtrssince 2019-Q1
Decreased
0
ASNDASND
ADR

ASCENDIS PHARMA A/S

2M$189.8M7.9%$117.47-18.12%
3 qtrssince 2019-Q1
Unchanged
0

BIOMARIN PHARMACEUTICAL INC

2.4M$164.3M6.9%$84.82-19.46%
3 qtrssince 2019-Q1
Increased
69
AMRNAMRN
ADR

AMARIN CORP PLC

8.5M$129.2M5.4%———
Increased
67

SAREPTA THERAPEUTICS INC

1.7M$126.4M5.3%$115.87-35.27%
3 qtrssince 2019-Q1
Increased
70

HORIZON THERAPEUTICS PUB L

4M$108.9M4.5%——
2 qtrssince 2019-Q2
Unchanged
0
ARGXARGX
ADR

ARGENX SE

835,000$95.2M4.0%$124.84-8.72%
3 qtrssince 2019-Q1
Decreased
0
FOLDFOLDDelisted

AMICUS THERAPEUTICS INC

11.1M$89M3.7%$13.00-37.93%
3 qtrssince 2019-Q1
Increased
62
MYOKMYOKDelisted

MYOKARDIA INC

1.6M$81M3.4%——
3 qtrssince 2019-Q1
Increased
63
ZGNXZGNXDelisted

ZOGENIX INC

1.9M$75.1M3.1%——
3 qtrssince 2019-Q1
Decreased
0
ATNXATNXDelisted

ATHENEX INC

5.9M$71.7M3.0%——
2 qtrssince 2019-Q2
Increased
64
TCDAQTCDAQDelisted

TRICIDA INC

2.2M$67.9M2.8%——
3 qtrssince 2019-Q1
Unchanged
0

PACIRA BIOSCIENCES INC COM

1.6M$60.9M2.5%$39.52-8.11%
3 qtrssince 2019-Q1
Increased
83

KARYOPHARM THERAPEUTICS INC

6.1M$58.2M2.4%———
New
77

GLOBAL BLOOD THERAPEUTICS IN

1M$48.5M2.0%——
3 qtrssince 2019-Q1
Increased
54

ACADIA PHARMACEUTICALS INC

887,500$31.9M1.3%$26.85+36.98%
3 qtrssince 2019-Q1
Decreased
0
BDSIBDSIDelisted

BIODELIVERY SCIENCES INTL INC

7.4M$31.3M1.3%——
3 qtrssince 2019-Q1
Unchanged
0

MADRIGAL PHARMACEUTICALS INC COM

360,000$31M1.3%$122.42-29.57%
3 qtrssince 2019-Q1
Unchanged
0
$2.4B
AUM
33
Positions
Q3 2019
Filing
HI score · 2.5/5
Quarterly 13F Value Change
+25%Q2'19$2.9B-17%Q3'19$2.4B
Activity profile
$ moved · Q3'19
New11%Increased37%Decreased35%Exited16%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 1.7 quarters
<1Q9%1-4Q91%1-2Y0%2Y+0%

Avoro Capital Advisors LLC manages $2.4B across 33 positions as of Q3 2019. Top holdings: MRTX (12.2%), IMMU (11.6%), IOVA (8.0%). Fund DNA: Concentrated Value. HoldingsIntel Score: 2.5/5.0.

Q3 2019 Summary

Added 3 new positions, exited 3, increased 9, trimmed 7. Top move: PCRX (INCREASED, conviction 83). Portfolio: $2.4B across 33 positions.

Top holdings by portfolio weight

Total AUM$2B
MRTX12.19%
IMMU11.62%
IOVA8.05%
ASND7.92%
BMRN6.85%
AMRN5.39%
SRPT5.27%
HZNP4.54%
ARGX3.97%
FOLD3.71%
Other3.38%

Portfolio allocation by GICS sector

Sectors2
Healthcare53.16%
Unknown46.84%

Behavioral investing profile

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Concentrated Value- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(2.5 / 5.0)
Holdings P&L53
Conviction47
Concentration100
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
4Q
OCULOCULOCULAR THERAPEUTIX INC COM
Q3 2025 → Q2 2026+5.1M shares+$54.5M
3Q
UTHRUTHRUNITED THERAPEUTICS CORP DEL
Q4 2025 → Q2 2026+755,555 shares+$657.3M
2Q
ARWRARWRARROWHEAD PHARMACEUTICALS IN
Q1 2026 → Q2 2026+730,555 shares+$220.2M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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