Avoro Capital Advisors LLCAvoro Capital Advisors LLC

Institutional investor · Portfolio as of Q2 2020

SEC EDGAR SourceSEC Filings

Top Holdings45 positions

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Activity:
Stock
Shares
Value
Weight
Avg Buy
Est. P&L
Held
Conviction
IMMUIMMUDelisted

IMMUNOMEDICS INC

26.3M$930.3M18.4%
6 qtrssince 2019-Q1
Increased
67
MRTXMRTXDelisted

MIRATI THERAPEUTICS INC

4.3M$489.4M9.7%
6 qtrssince 2019-Q1
Increased
64
HZNPHZNPDelisted

HORIZON THERAPEUTICS PLC

6M$333.5M6.6%
5 qtrssince 2019-Q2
Increased
77

IOVANCE BIOTHERAPEUTICS INC

10.4M$284.4M5.6%$12.44+118.65%
6 qtrssince 2019-Q1
Increased
70

AVI BIOPHARMA INC

1.7M$268.6M5.3%$118.96+36.78%
6 qtrssince 2019-Q1
Increased
64
ASNDASND
ADR

ASCENDIS PHARMA A/S

1.8M$258.8M5.1%$117.47+23.61%
6 qtrssince 2019-Q1
Decreased
0

BIOMARIN PHARMACEUTICAL INC

1.9M$228.2M4.5%$84.82+44.05%
6 qtrssince 2019-Q1
Decreased
0
ARGXARGX
ADR

ARGENX SE - ADR

970,000$218.5M4.3%$132.11+69.02%
6 qtrssince 2019-Q1
Increased
59
MYOKMYOKDelisted

MYOKARDIA INC

1.9M$181.6M3.6%
6 qtrssince 2019-Q1
Increased
72
FOLDFOLDDelisted

AMICUS THERAPEUTICS INC

11M$165.9M3.3%$12.98+19.70%
6 qtrssince 2019-Q1
Increased
57
ADVMADVMDelisted

ADVERUM BIOTECHNOLOGIES INC

7.6M$158.4M3.1%
MRSNMRSNDelisted

MERSANA THERAPEUTICS INC

6.5M$152.1M3.0%$557.000.00%
1 qtr
New
85

Karyopharm Therapeutics Inc.

7M$132.6M2.6%
CNSTCNSTDelisted

CONSTELLATION PHARMCETICLS I

4M$120.2M2.4%
3 qtrssince 2019-Q4
Increased
58
DCPHDCPHDelisted

DECIPHERA PHARMACEUTICALS IN

1.9M$111.1M2.2%
3 qtrssince 2019-Q4
Decreased
0
ADAPYADAPYDelisted
ADR

ADAPTIMMUNE THERAPEUTICS PLC Spon ADS Each Rep 6 Ord Shs

10M$100.1M2.0%$9.290.00%
1 qtr
New
69
XLRNXLRNDelisted

ACCELERON PHARMA INC

1M$99.1M2.0%
2 qtrssince 2020-Q1
Increased
57

uniQure N.V.

1.5M$67.6M1.3%$64.81-29.44%
4 qtrssince 2019-Q3
Decreased
0

RELMADA THERAPEUTICS INC

1.4M$63.8M1.3%$33.94+26.89%
2 qtrssince 2020-Q1
Increased
58
ZGNXZGNXDelisted

ZOGENIX INC

2.3M$60.8M1.2%
6 qtrssince 2019-Q1
Decreased
0
$5.1B
AUM
45
Positions
Q2 2020
Filing
Rating · 1.5
Quarterly Portfolio Change
+25%Q2'19$2.9B-17%Q3'19$2.4B+42%Q4'19$3.4B-13%Q1'20$3B+71%Q2'20$5.1B
Activity profile
$ moved · Q2'20
New18%Increased68%Decreased12%Exited3%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 3.4 quarters
<1Q20%1-4Q24%1-2Y47%2Y+9%

Avoro Capital Advisors LLC manages $5.1B across 45 positions as of Q2 2020. Top holdings: IMMU (18.4%), MRTX (9.7%), HZNP (6.6%). Fund DNA: Balanced Allocator. HoldingsIntel Rating: 1.5/5.0.

Q2 2020 Summary

Active quarter - 8 new positions, 5 exits, 18 increased. Top move: MRSN (NEW, conviction 85). Portfolio: $5.1B across 45 positions.

Top holdings by portfolio weight

Total AUM$5B
IMMU18.39%
MRTX9.68%
HZNP6.59%
IOVA5.62%
SRPT5.31%
ASND5.12%
BMRN4.51%
ARGX4.32%
MYOK3.59%
FOLD3.28%
Other3.13%

Portfolio allocation by GICS sector

Sectors2
Unknown55.30%
Healthcare44.70%

Behavioral investing profile

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Balanced Allocator- primarily Unknown, Healthcare
Compare DNA across all funds
7-dimension quality assessment
Below Average(1.5 / 5.0)
Track RecordNo data
Conviction47
Concentration100
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

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Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

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4Q
OCULOCULOCULAR THERAPEUTIX INC
Q3 2025 Q2 2026+5.1M shares+$54.5M
3Q
UTHRUTHRUNITED THERAPEUTICS CORP
Q4 2025 Q2 2026+755,555 shares+$657.3M
2Q
ARWRARWRARROWHEAD PHARMACEUTICALS IN
Q1 2026 Q2 2026+730,555 shares+$220.2M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

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