Avoro Capital Advisors LLCAvoro Capital Advisors LLC

Institutional investor · Portfolio as of Q1 2024

SEC EDGAR SourceSEC Filings

Top Holdings46 positions

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Activity:
Stock
Shares
Value
Weight
Avg Buy
Est. P&L
Held
Conviction

UNITED THERAPEUTICS CORP

2.9M$656.7M7.7%$151.50+51.63%
14 qtrssince 2020-Q4
Unchanged
0
APLSAPLSDelisted

APELLIS PHARMACEUTICALS INC

11.1M$653.1M7.6%$43.88+33.95%
13 qtrssince 2021-Q1
Unchanged
0
ASNDASND
ADR

ASCENDIS PHARMA A/S

4M$599.6M7.0%$123.04+22.86%
12 qtrssince 2021-Q2
Increased
66

AVI BIOPHARMA INC

4.3M$562.4M6.6%$107.06+20.92%
21 qtrssince 2019-Q1
Unchanged
0

MADRIGAL PHARMACEUTICALS INC

1.9M$519.2M6.1%$150.17+77.83%
21 qtrssince 2019-Q1
Increased
64
ARGXARGX
ADR

ARGENX SE - ADR

1.2M$487.6M5.7%$224.78+75.16%
21 qtrssince 2019-Q1
Increased
62

Krystal Biotech, Inc.

2.6M$454.7M5.3%$85.59+107.88%
10 qtrssince 2021-Q4
Decreased
0
XBIXBI
ETF

SPDR S&P BIOTECH ETF

4.3M$408M4.8%$88.83+6.27%
2 qtrssince 2023-Q4
Decreased
0

BIOMARIN PHARMACEUTICAL INC

4.4M$381.2M4.4%$87.08+0.30%
21 qtrssince 2019-Q1
Increased
59
FOLDFOLDDelisted

AMICUS THERAPEUTICS INC

27.4M$322.8M3.8%$11.07+6.42%
21 qtrssince 2019-Q1
Unchanged
0
CERECEREDelisted

CEREVEL THERAPEUTICS HLDNG I

7.6M$319.4M3.7%
3 qtrssince 2023-Q3
Unchanged
0

VIKING THERAPEUTICS INC

3.6M$294.4M3.4%$82.00-59.52%
1 qtr
New
87

ARROWHEAD PHARMACEUTICALS IN

8.6M$244.7M2.9%$29.00-1.37%
4 qtrssince 2023-Q2
Increased
86

XENON PHARMACEUTICALS INC

5.7M$243.9M2.8%$21.21+102.94%
21 qtrssince 2019-Q1
Unchanged
0
ALPNALPNDelisted

ALPINE IMMUNE SCIENCES INC

5.8M$228.9M2.7%
1 qtr
New
80

VERA THERAPEUTICS INC

5.3M$227M2.6%$43.120.00%
1 qtr
New
80

IOVANCE BIOTHERAPEUTICS INC

11.7M$173.4M2.0%$15.03-1.40%
21 qtrssince 2019-Q1
Increased
80
ITCIITCIDelisted

INTRA-CELLULAR THERAPIES INC

2.5M$171.3M2.0%
2 qtrssince 2023-Q4
Increased
54

KYMERA THERAPEUTICS INC

3.9M$156.3M1.8%$30.08+33.63%
11 qtrssince 2021-Q3
Increased
50
5.8M$148.7M1.7%$24.04+6.14%
16 qtrssince 2020-Q2
Increased
78
$8.6B
AUM
46
Positions
Q1 2024
Filing
Rating · 1.5
Quarterly Portfolio Change
+24%Q4'22$6.7B+1%Q1'23$6.7B+9%Q2'23$7.4B-13%Q3'23$6.4B+13%Q4'23$7.2B+18%Q1'24$8.6B
Activity profile
$ moved · Q1'24
New35%Increased31%Decreased10%Exited24%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 2.2 years
<1Q22%1-4Q20%1-2Y2%2Y+57%

Avoro Capital Advisors LLC manages $8.6B across 46 positions as of Q1 2024. Top holdings: UTHR (7.7%), APLS (7.6%), ASND (7.0%). Fund DNA: Balanced Allocator. HoldingsIntel Rating: 1.5/5.0.

Q1 2024 Summary

Active quarter - 11 new positions, 7 exits, 15 increased. Top move: VKTX (NEW, conviction 87). Portfolio: $8.6B across 46 positions.

Top holdings by portfolio weight

Total AUM$9B
UTHR7.66%
APLS7.62%
ASND6.99%
SRPT6.56%
MDGL6.06%
ARGX5.69%
KRYS5.30%
XBI4.76%
BMRN4.45%
FOLD3.76%
Other3.73%

Portfolio allocation by GICS sector

Sectors2
Healthcare85.75%
Unknown14.25%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension quality assessment
Below Average(1.5 / 5.0)
Track RecordNo data
Conviction47
Concentration100
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
4Q
OCULOCULOCULAR THERAPEUTIX INC
Q3 2025 Q2 2026+5.1M shares+$54.5M
3Q
UTHRUTHRUNITED THERAPEUTICS CORP
Q4 2025 Q2 2026+755,555 shares+$657.3M
2Q
ARWRARWRARROWHEAD PHARMACEUTICALS IN
Q1 2026 Q2 2026+730,555 shares+$220.2M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

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