BAKER BROS. ADVISORS LPBAKER BROS. ADVISORS LP

Institutional investor · Portfolio as of Q1 2019

Top Holdings96 positions

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Activity:
51M$3.7B23.9%——
1 qtr
First report
0

INCYTE CORP

34.3M$2.9B18.9%$86.010.00%
1 qtr
First report
0
ONCONC
ADR

BEONE MEDICINES LTD

12M$1.6B10.1%$132.000.00%
1 qtr
First report
0
ALXNALXNDelisted

ALEXION PHARMACEUTICALS INC

8.6M$1.2B7.4%——
1 qtr
First report
0

ACADIA PHARMACEUTICALS INC

39.7M$1.1B6.8%$26.850.00%
1 qtr
First report
0
AMRNAMRN
ADR

AMARIN CORP PLC

43.2M$897M5.7%$415.200.00%
1 qtr
First report
0
GHDXGHDXDelisted

GENOMIC HEALTH INC

10.2M$714.4M4.6%——
1 qtr
First report
0

BIOMARIN PHARMACEUTICAL INC

7.6M$674.2M4.3%$88.830.00%
1 qtr
First report
0
ASNDASND
ADR

ASCENDIS PHARMA A/S

3.4M$399M2.6%$117.700.00%
1 qtr
First report
0
MRTXMRTXDelisted

MIRATI THERAPEUTICS INC

2.5M$184.2M1.2%——
1 qtr
First report
0

MADRIGAL PHARMACEUTICALS INC

1.2M$146.5M0.9%$125.260.00%
1 qtr
First report
0
ARGXARGX
ADR

ARGENX SE

1M$127.3M0.8%$124.840.00%
1 qtr
First report
0

BIOCRYST PHARMACEUTICALS INC

15.1M$123.1M0.8%$8.140.00%
1 qtr
First report
0

HERON THERAPEUTICS INC

5M$122.6M0.8%$24.440.00%
1 qtr
First report
0
CMCMTADelisted

Clementia Pharmaceuticals Inc.

3.7M$97.2M0.6%——
1 qtr
First report
0

NEUROCRINE BIOSCIENCES INC

1.1M$96.8M0.6%$88.100.00%
1 qtr
First report
0
3.8M$93.7M0.6%——
1 qtr
First report
0
NVTAQNVTAQDelisted

Invitae Corp

3.9M$91.4M0.6%——
1 qtr
First report
0
ONCEONCEDelisted

SPARK THERAPEUTICS INC

751,927$85.6M0.5%——
1 qtr
First report
0
CBAYCBAYDelisted

CYMABAY THERAPEUTICS INC

5.7M$75.8M0.5%——
1 qtr
First report
0
$15.6B
AUM
96
Positions
Q1 2019
Filing
HI score · 3.0/5
Quarterly 13F Value Change
Not enough history yet
Activity profile
Q1'19

First report: nothing earlier to compare

Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
<1Q100%1-4Q0%1-2Y0%2Y+0%

BAKER BROS. ADVISORS LP manages $15.6B across 96 positions as of Q1 2019. Top holdings: SGEN (23.9%), INCY (18.9%), ONC (10.1%). Fund DNA: Concentrated Value. HoldingsIntel Score: 3/5.0.

Q1 2019 Summary

First quarter we have for this fund: 96 positions, nothing earlier to compare. No standout high-conviction moves this quarter. Portfolio: $15.6B across 96 positions.

Top holdings by portfolio weight

Total AUM$16B
SGEN23.93%
INCY18.87%
ONC10.11%
ALXN7.41%
ACAD6.83%
AMRN5.74%
GHDX4.57%
BMRN4.32%
ASND2.55%
MRTX1.18%
Other0.94%

Portfolio allocation by GICS sector

Sectors2
Healthcare57.19%
Unknown42.81%

Behavioral investing profile

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Concentrated Value- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(3.0 / 5.0)
Holdings P&L46
Conviction36
Concentration100
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Accumulation Streaks

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7Q
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Q4 2024 → Q2 2026+23,310 shares+$1.5B
5Q
IDYAIDYAIDEAYA BIOSCIENCES INC
Q2 2025 → Q2 2026+3.9M shares+$169.3M
3Q
DSGNDSGNDESIGN THERAPEUTICS INC
Q4 2025 → Q2 2026+965,548 shares+$25.9M
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Famous Investors' Portfolios

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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

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