RA CAPITAL MANAGEMENT, L.P.RA CAPITAL MANAGEMENT, L.P.

Institutional investor · Portfolio as of Q2 2021

Top Holdings92 positions

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Activity:
ASNDASND
ADR

ASCENDIS PHARMA A/S

6.8M$895.4M14.4%$89.68+49.73%
11 qtrssince 2018-Q4
Increased
66

Novavax Inc

2.6M$543.5M8.7%$107.78+93.86%
5 qtrssince 2020-Q2
Decreased
0
FMTXFMTXDelisted

FORMA THERAPEUTICS HLDGS INC

9M$224.3M3.6%——
5 qtrssince 2020-Q2
Unchanged
0

JANUX THERAPEUTICS INC

8.7M$216.3M3.5%$25.370.00%
1 qtr
New
85

VOR BIOPHARMA INC

11.1M$207.4M3.3%$781.20-50.00%
2 qtrssince 2021-Q1
Unchanged
0
8.3M$188.7M3.0%——
1 qtr
New
84

Nkarta Inc

5.6M$177.6M2.9%$30.36-2.24%
4 qtrssince 2020-Q3
Unchanged
0

MACROGENICS INC

5.9M$159.6M2.6%$28.28-5.58%
5 qtrssince 2020-Q2
Increased
62
7M$136.5M2.2%$18.13+7.46%
2 qtrssince 2021-Q1
Increased
84

TG Therapeutics Inc

3.3M$129.7M2.1%$8.58+338.13%
11 qtrssince 2018-Q4
Decreased
0

ImmunoGen Inc

18.4M$121.4M1.9%——
4 qtrssince 2020-Q3
Unchanged
0

ATEA PHARMACEUTICALS INC

5.4M$115.3M1.9%$41.71-41.48%
3 qtrssince 2020-Q4
Unchanged
0
ITOSITOSDelisted

ITEOS THERAPEUTICS INC

4.4M$113.3M1.8%——
4 qtrssince 2020-Q3
Increased
47
DAWNDAWNDelisted

DAY ONE BIOPHARMACEUTICALS I

5M$113.1M1.8%$22.210.00%
1 qtr
New
69

AXSOME THERAPEUTICS INC

1.7M$111.7M1.8%$50.95+36.71%
10 qtrssince 2019-Q1
Unchanged
0

PHATHOM PHARMACEUTICALS INC

3.1M$105.4M1.7%$32.43+4.84%
7 qtrssince 2019-Q4
Unchanged
0

INSTIL BIO INC

4.9M$94.1M1.5%$484.80-24.30%
2 qtrssince 2021-Q1
Unchanged
0

Rocket Pharmaceuticals Inc

2.1M$93.3M1.5%$56.05-22.69%
3 qtrssince 2020-Q4
Unchanged
0
ETNBETNBDelisted

89bio Inc

5M$92.9M1.5%——
7 qtrssince 2019-Q4
Increased
49
ZGNXZGNXDelisted

Zogenix Inc

5.3M$91.3M1.5%——
11 qtrssince 2018-Q4
Unchanged
0
$6.2B
AUM
92
Positions
Q2 2021
Filing
HI score · 2.5/5
Quarterly 13F Value Change
-4%Q1'20$3.2B+62%Q2'20$5.1B+7%Q3'20$5.5B+31%Q4'20$7.2B-7%Q1'21$6.6B-6%Q2'21$6.2B
Activity profile
$ moved · Q2'21
New52%Increased17%Decreased12%Exited19%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 3.1 quarters
<1Q21%1-4Q47%1-2Y21%2Y+12%

RA CAPITAL MANAGEMENT, L.P. manages $6.2B across 92 positions as of Q2 2021. Top holdings: ASND (14.4%), NVAX (8.7%), FMTX (3.6%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 2.5/5.0.

Q2 2021 Summary

Active quarter - 20 new positions, 10 exits, 8 increased. Top move: JANX (NEW, conviction 85). Portfolio: $6.2B across 92 positions.

Top holdings by portfolio weight

Total AUM$6B
ASND14.37%
NVAX8.72%
FMTX3.60%
JANX3.47%
VOR3.33%
AEROVATE THE3.03%
NKTX2.85%
MGNX2.56%
CNTB2.19%
TGTX2.08%
Other1.95%

Portfolio allocation by GICS sector

Sectors2
Healthcare75.21%
Unknown24.79%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(2.5 / 5.0)
Holdings P&L31
Conviction41
Concentration91
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
2Q
SLDBSLDBSOLID BIOSCIENCES INC
Q1 2026 → Q2 2026+6.2M shares+$87.5M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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