RA CAPITAL MANAGEMENT, L.P.RA CAPITAL MANAGEMENT, L.P.

Institutional investor · Portfolio as of Q2 2021

SEC EDGAR SourceSEC Filings

Top Holdings92 positions

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Activity:
Stock
Shares
Value
Weight
Avg Buy
Est. P&L
Held
Conviction
ASNDASND
ADR

ASCENDIS PHARMA A/S

6.8M$895.4M14.4%$89.68+49.73%
11 qtrssince 2018-Q4
Increased
66

NOVAVAX INC

2.6M$543.5M8.7%$107.78+93.86%
5 qtrssince 2020-Q2
Decreased
0
FMTXFMTXDelisted

FORMA THERAPEUTICS HLDGS INC

9M$224.3M3.6%
5 qtrssince 2020-Q2
Unchanged
0

JANUX THERAPEUTICS INC

8.7M$216.3M3.5%$25.370.00%
1 qtr
New
85

Vor Biopharma Inc.

11.1M$207.4M3.3%
8.3M$188.7M3.0%
1 qtr
New
84

NKARTA INC

5.6M$177.6M2.9%$30.36-2.24%
4 qtrssince 2020-Q3
Unchanged
0

MACROGENICS INC

5.9M$159.6M2.6%$28.28-5.58%
5 qtrssince 2020-Q2
Increased
62
7M$136.5M2.2%$18.13+7.46%
2 qtrssince 2021-Q1
Increased
84

TG Therapeutics, Inc.

3.3M$129.7M2.1%$8.58+338.13%
11 qtrssince 2018-Q4
Decreased
0

IMMUNOGEN INC

18.4M$121.4M1.9%
4 qtrssince 2020-Q3
Unchanged
0

ATEA PHARMACEUTICALS INC

5.4M$115.3M1.9%$41.71-41.48%
3 qtrssince 2020-Q4
Unchanged
0
ITOSITOSDelisted

ITEOS THERAPEUTICS INC

4.4M$113.3M1.8%
4 qtrssince 2020-Q3
Increased
47
DAWNDAWNDelisted

DAY ONE BIOPHARMACEUTICALS I

5M$113.1M1.8%$22.210.00%
1 qtr
New
69

AXSOME THERAPEUTICS INC

1.7M$111.7M1.8%$50.95+36.71%
10 qtrssince 2019-Q1
Unchanged
0

PHATHOM PHARMACEUTICALS INC

3.1M$105.4M1.7%$32.43+4.84%
7 qtrssince 2019-Q4
Unchanged
0

Instil Bio, Inc.

4.9M$94.1M1.5%

ROCKET PHARMACEUTICALS INC

2.1M$93.3M1.5%$56.05-22.69%
3 qtrssince 2020-Q4
Unchanged
0
ETNBETNBDelisted

89BIO INC

5M$92.9M1.5%
7 qtrssince 2019-Q4
Increased
49
ZGNXZGNXDelisted

ZOGENIX INC

5.3M$91.3M1.5%
11 qtrssince 2018-Q4
Unchanged
0
$6.2B
AUM
92
Positions
Q2 2021
Filing
Rating · 2.0
Quarterly Portfolio Change
-4%Q1'20$3.2B+62%Q2'20$5.1B+7%Q3'20$5.5B+31%Q4'20$7.2B-7%Q1'21$6.6B-6%Q2'21$6.2B
Activity profile
$ moved · Q2'21
New52%Increased17%Decreased12%Exited19%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 3.1 quarters
<1Q21%1-4Q47%1-2Y21%2Y+12%

RA CAPITAL MANAGEMENT, L.P. manages $6.2B across 92 positions as of Q2 2021. Top holdings: ASND (14.4%), NVAX (8.7%), FMTX (3.6%). Fund DNA: Balanced Allocator. HoldingsIntel Rating: 2/5.0.

Q2 2021 Summary

Active quarter - 20 new positions, 10 exits, 8 increased. Top move: JANX (NEW, conviction 85). Portfolio: $6.2B across 92 positions.

Top holdings by portfolio weight

Total AUM$6B
ASND14.37%
NVAX8.72%
FMTX3.60%
JANX3.47%
VOR3.33%
AEROVATE THE3.03%
NKTX2.85%
MGNX2.56%
CNTB2.19%
TGTX2.08%
Other1.95%

Portfolio allocation by GICS sector

Sectors2
Healthcare75.21%
Unknown24.79%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension quality assessment
Below Average(2.0 / 5.0)
Track Record47
Conviction42
Concentration91
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
2Q
SLDBSLDBSOLID BIOSCIENCES INC
Q1 2026 Q2 2026+6.2M shares+$87.5M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

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