RA CAPITAL MANAGEMENT, L.P.RA CAPITAL MANAGEMENT, L.P.

Institutional investor · Portfolio as of Q2 2019

Top Holdings25 positions

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Activity:
ASNDASND
ADR

ASCENDIS PHARMA A/S

4.1M$475.9M25.5%$59.89+92.27%
3 qtrssince 2018-Q4
Unchanged
0

WAVE LIFE SCIENCES LTD

7.8M$202.9M10.9%$42.17-38.14%
3 qtrssince 2018-Q4
Unchanged
0
ZGNXZGNXDelisted

Zogenix Inc

3.7M$177.9M9.5%——
3 qtrssince 2018-Q4
Increased
85
RARXRARXDelisted

RA PHARMACEUTICALS INC

4.9M$137M7.4%——
3 qtrssince 2018-Q4
Unchanged
0
THORTHORDelisted

SYNTHORX INC

9.7M$131.4M7.1%——
3 qtrssince 2018-Q4
Unchanged
0
EIDXEIDXDelisted

EIDOS THERAPEUTICS INC

2.2M$112.7M6.1%——
3 qtrssince 2018-Q4
Unchanged
0
ORTXORTXDelisted
ADR

ORCHARD THERAPEUTICS PLC

5.1M$71.5M3.8%——
3 qtrssince 2018-Q4
Unchanged
0

TG Therapeutics Inc

6.9M$59.5M3.2%$3.98+117.34%
3 qtrssince 2018-Q4
Decreased
0

MYOVANT SCIENCES LTD

6.5M$59.2M3.2%——
3 qtrssince 2018-Q4
Increased
85
CRNXCRNXDelisted

CRINETICS PHARMACEUTICALS IN

1.9M$46.9M2.5%$30.51-18.06%
3 qtrssince 2018-Q4
Unchanged
0

Rhythm Pharmaceuticals Inc

1.9M$41.5M2.2%$26.88-18.15%
3 qtrssince 2018-Q4
Unchanged
0
DRNADRNADelisted

Dicerna Pharmaceuticals Inc

2.5M$38.7M2.1%——
3 qtrssince 2018-Q4
Unchanged
0

Arvinas Inc

1.7M$37.1M2.0%$13.16+67.10%
3 qtrssince 2018-Q4
Decreased
0
PRVLPRVLDelisted

PREVAIL THERAPEUTICS INC

2.7M$36.2M1.9%——
1 qtr
New
67

AXSOME THERAPEUTICS INC

1.3M$34.5M1.9%$14.23+80.96%
2 qtrssince 2019-Q1
Decreased
0

STOKE THERAPEUTICS INC

1.1M$32.7M1.8%$29.170.00%
1 qtr
New
67

KALA PHARMACEUTICALS INC

4.5M$28.9M1.6%$251.00+27.09%
3 qtrssince 2018-Q4
Unchanged
0
SWAVSWAVDelisted

Shockwave Medical Inc

495,608$28.3M1.5%——
2 qtrssince 2019-Q1
Unchanged
0

PRECISION BIOSCIENCES INC

1.8M$24.4M1.3%$538.50-26.18%
2 qtrssince 2019-Q1
Unchanged
0
2.7M$21.3M1.1%——
3 qtrssince 2018-Q4
Unchanged
0
$1.9B
AUM
25
Positions
Q2 2019
Filing
HI score · 2.5/5
Quarterly 13F Value Change
+35%Q1'19$2.3B-20%Q2'19$1.9B
Activity profile
$ moved · Q2'19
New15%Increased14%Decreased4%Exited67%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 1.5 quarters
<1Q16%1-4Q84%1-2Y0%2Y+0%

RA CAPITAL MANAGEMENT, L.P. manages $1.9B across 25 positions as of Q2 2019. Top holdings: ASND (25.5%), WVE (10.9%), ZGNX (9.5%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 2.5/5.0.

Q2 2019 Summary

Active quarter - 4 new positions, 8 exits, 4 increased. Top move: ZGNX (INCREASED, conviction 85). Portfolio: $1.9B across 25 positions.

Top holdings by portfolio weight

Total AUM$2B
ASND25.54%
WVE10.89%
ZGNX9.55%
RARX7.35%
THOR7.05%
EIDX6.05%
ORTX3.84%
TGTX3.19%
MYOV3.18%
CRNX2.52%
Other2.23%

Portfolio allocation by GICS sector

Sectors2
Healthcare54.77%
Unknown45.23%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(2.5 / 5.0)
Holdings P&L31
Conviction41
Concentration91
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
2Q
SLDBSLDBSOLID BIOSCIENCES INC COM NEW
Q1 2026 → Q2 2026+6.2M shares+$87.5M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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