RA CAPITAL MANAGEMENT, L.P.RA CAPITAL MANAGEMENT, L.P.

Institutional investor · Portfolio as of Q1 2020

Top Holdings48 positions

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Activity:
ASNDASND
ADR

ASCENDIS PHARMA A/S

4.9M$553.5M17.5%$69.04+68.02%
6 qtrssince 2018-Q4
Increased
72
RARXRARXDelisted

RA PHARMACEUTICALS INC

4.9M$233.2M7.4%——
6 qtrssince 2018-Q4
Unchanged
0
4.2M$167.8M5.3%——
2 qtrssince 2019-Q4
Increased
76

ARVINAS INC COM

3.7M$148M4.7%$29.09+41.25%
6 qtrssince 2018-Q4
Unchanged
0
ZGNXZGNXDelisted

ZOGENIX INC

5.3M$130.5M4.1%——
6 qtrssince 2018-Q4
Increased
90

AXSOME THERAPEUTICS INC

1.9M$112M3.5%$49.21+17.02%
5 qtrssince 2019-Q1
Increased
90
EIDXEIDXDelisted

EIDOS THERAPEUTICS INC

2.2M$105.9M3.3%——
6 qtrssince 2018-Q4
Unchanged
0

TG Therapeutics Inc

10.4M$102.2M3.2%$6.27+64.50%
6 qtrssince 2018-Q4
Increased
59
STSASTSADelisted

SATSUMA PHARMACEUTICALS INC

4.7M$100.8M3.2%——
3 qtrssince 2019-Q3
Unchanged
0

ALECTOR INC COM

4.1M$99.6M3.1%$23.10+6.06%
5 qtrssince 2019-Q1
Increased
90

PHATHOM PHARMACEUTICALS INC

3.7M$95.7M3.0%$32.39-20.16%
2 qtrssince 2019-Q4
Increased
57

KALA BIO, Inc.

10.9M$95.6M3.0%———
Increased
90

RHYTHM PHARMACEUTICALS INC

5.4M$82.5M2.6%$23.93-36.41%
6 qtrssince 2018-Q4
Unchanged
0
ETNBETNBDelisted

89BIO INC

3.2M$79.8M2.5%——
2 qtrssince 2019-Q4
Unchanged
0

EXELIXIS INC

4.5M$77.9M2.5%$17.77+236.86%
1 qtr
New
78

WAVE LIFE SCIENCES LTD

7.8M$72.9M2.3%$42.17-78.19%
6 qtrssince 2018-Q4
Unchanged
0
ADVMADVMDelisted

ADVERUM BIOTECHNOLOGIES INC

7.3M$71.1M2.2%———
New
78
MNTAMNTADelisted

MOMENTA PHARMACEUTICALS INC

2.5M$68.9M2.2%——
2 qtrssince 2019-Q4
Increased
78

BLACK DIAMOND THERAPEUTICS INC COM

2.6M$64.6M2.0%$25.400.00%
1 qtr
New
77
??RETROPHIN INCDelisted
4.2M$60.8M1.9%———
Decreased
0
$3.2B
AUM
48
Positions
Q1 2020
Filing
HI score · 2.5/5
Quarterly 13F Value Change
+35%Q1'19$2.3B-20%Q2'19$1.9B-10%Q3'19$1.7B+96%Q4'19$3.3B-4%Q1'20$3.2B
Activity profile
$ moved · Q1'20
New28%Increased26%Decreased1%Exited45%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 2.1 quarters
<1Q38%1-4Q29%1-2Y33%2Y+0%

RA CAPITAL MANAGEMENT, L.P. manages $3.2B across 48 positions as of Q1 2020. Top holdings: ASND (17.5%), RARX (7.4%), CHEMOCENTRYX INC (5.3%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 2.5/5.0.

Q1 2020 Summary

Active quarter - 18 new positions, 4 exits, 15 increased. Top move: ZGNX (INCREASED, conviction 90). Portfolio: $3.2B across 48 positions.

Top holdings by portfolio weight

Total AUM$3B
ASND17.48%
RARX7.37%
CHEMOCENTRYX5.30%
ARVN4.68%
ZGNX4.12%
AXSM3.54%
EIDX3.35%
TGTX3.23%
STSA3.18%
ALEC3.15%
Other3.02%

Portfolio allocation by GICS sector

Sectors2
Healthcare60.17%
Unknown39.83%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(2.5 / 5.0)
Holdings P&L29
Conviction41
Concentration91
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
2Q
SLDBSLDBSOLID BIOSCIENCES INC
Q1 2026 → Q2 2026+6.2M shares+$87.5M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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