RA CAPITAL MANAGEMENT, L.P.RA CAPITAL MANAGEMENT, L.P.

Institutional investor · Portfolio as of Q1 2019

Top Holdings29 positions

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Activity:
ASNDASND
ADR

ASCENDIS PHARMA A/S

4.1M$486.4M21.0%$59.89+96.53%
2 qtrssince 2018-Q4
Decreased
0

WAVE LIFE SCIENCES LTD

7.8M$302.1M13.0%$42.17-7.88%
2 qtrssince 2018-Q4
Increased
63
THORTHORDelisted

SYNTHORX INC

9.7M$198.1M8.5%——
2 qtrssince 2018-Q4
Unchanged
0
ZGNXZGNXDelisted

ZOGENIX INC

2.4M$131M5.7%——
2 qtrssince 2018-Q4
Unchanged
0
RARXRARXDelisted

RA PHARMACEUTICALS INC

4.9M$108.8M4.7%——
2 qtrssince 2018-Q4
Unchanged
0

INFLARX NV

2.8M$106.2M4.6%$36.74+2.87%
2 qtrssince 2018-Q4
Increased
72
ORTXORTXDelisted
ADR

ORCHARD THERAPEUTICS PLC

5.1M$91.3M3.9%——
2 qtrssince 2018-Q4
Increased
59
EIDXEIDXDelisted

EIDOS THERAPEUTICS INC

2.2M$91.1M3.9%——
2 qtrssince 2018-Q4
Unchanged
0

MYOVANT SCIENCES LTD

3.5M$84.6M3.6%——
2 qtrssince 2018-Q4
Decreased
0

BIOCRYST PHARMACEUTICALS INC

8.7M$70.5M3.0%$8.07+0.87%
2 qtrssince 2018-Q4
Decreased
0

TG THERAPEUTICS INC

8.2M$65.9M2.8%$3.98+102.01%
2 qtrssince 2018-Q4
Unchanged
0

SAGE THERAPEUTICS INC

384,001$61.1M2.6%——
1 qtr
New
77

RHYTHM PHARMACEUTICALS INC

1.9M$51.7M2.2%$26.88+1.97%
2 qtrssince 2018-Q4
Decreased
0

AXSOME THERAPEUTICS INC.

3.3M$46.9M2.0%$14.230.00%
1 qtr
New
77
CRNXCRNXDelisted

CRINETICS PHARMACEUTICALS IN

1.9M$42.7M1.8%$29.99-24.11%
2 qtrssince 2018-Q4
Unchanged
0
KALVKALVDelisted

KALVISTA PHARMACEUTICALS INC

1.4M$41.2M1.8%——
2 qtrssince 2018-Q4
Unchanged
0

KALA PHARMACEUTICALS INC

4.5M$37.5M1.6%$12,225.00+69.12%
2 qtrssince 2018-Q4
Unchanged
0
MNTAMNTADelisted

MOMENTA PHARMACEUTICALS INC

2.6M$37.3M1.6%——
2 qtrssince 2018-Q4
Increased
47
DRNADRNADelisted

DICERNA PHARMACEUTICALS INC

2.5M$36M1.6%——
2 qtrssince 2018-Q4
Unchanged
0
EIGREIGRDelisted

EIGER BIOPHARMACEUTICALS INC

2.4M$33.8M1.5%——
2 qtrssince 2018-Q4
Unchanged
0
$2.3B
AUM
29
Positions
Q1 2019
Filing
HI score · 2.0/5
Quarterly 13F Value Change
Not enough history yet
Activity profile
$ moved · Q1'19
New32%Increased12%Decreased48%Exited8%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg <1 quarter
<1Q21%1-4Q79%1-2Y0%2Y+0%

RA CAPITAL MANAGEMENT, L.P. manages $2.3B across 29 positions as of Q1 2019. Top holdings: ASND (21.0%), WVE (13.0%), THOR (8.5%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 2/5.0.

Q1 2019 Summary

Active quarter - 6 new positions, 2 exits, 4 increased. Top move: SAGE (NEW, conviction 77). Portfolio: $2.3B across 29 positions.

Top holdings by portfolio weight

Total AUM$2B
ASND20.97%
WVE13.03%
THOR8.54%
ZGNX5.65%
RARX4.69%
IFRX4.58%
ORTX3.94%
EIDX3.93%
MYOV3.65%
BCRX3.04%
Other2.84%

Portfolio allocation by GICS sector

Sectors2
Healthcare59.94%
Unknown40.06%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Below Average(2.0 / 5.0)
Holdings P&L22
Conviction41
Concentration91
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
2Q
SLDBSLDBSOLID BIOSCIENCES INC
Q1 2026 → Q2 2026+6.2M shares+$87.5M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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