RA CAPITAL MANAGEMENT, L.P.RA CAPITAL MANAGEMENT, L.P.

Institutional investor · Portfolio as of Q3 2020

Top Holdings70 positions

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Activity:
ASNDASND
ADR

ASCENDIS PHARMA A/S

5.9M$912M16.7%$83.05+83.34%
8 qtrssince 2018-Q4
Increased
74
FMTXFMTXDelisted

FORMA THERAPEUTICS HLDGS INC

9M$449.1M8.2%——
2 qtrssince 2020-Q2
Unchanged
0
4.8M$264.5M4.8%——
4 qtrssince 2019-Q4
Unchanged
0

VAXCYTE INC

5.3M$260.9M4.8%$31.20+65.06%
2 qtrssince 2020-Q2
Decreased
0

TG Therapeutics Inc

8.8M$236.2M4.3%$8.58+204.86%
8 qtrssince 2018-Q4
Decreased
0

NKARTA INC COM

5.6M$168.5M3.1%$30.360.00%
1 qtr
New
84

AXSOME THERAPEUTICS INC

2M$145M2.7%$50.95+41.85%
7 qtrssince 2019-Q1
Unchanged
0

PHATHOM PHARMACEUTICALS INC

3.8M$140.3M2.6%$32.43+10.36%
4 qtrssince 2019-Q4
Unchanged
0

SERES THERAPEUTICS INC

4.8M$134.5M2.5%———
New
78

NOVAVAX INC COM NEW

1.2M$129.9M2.4%$83.61+29.11%
2 qtrssince 2020-Q2
Decreased
0
ETNBETNBDelisted

89BIO INC

4.7M$121.5M2.2%——
4 qtrssince 2019-Q4
Increased
71

RHYTHM PHARMACEUTICALS INC

5.1M$111.4M2.0%$23.93-9.46%
8 qtrssince 2018-Q4
Decreased
0

MACROGENICS INC COM

4.4M$110.2M2.0%$28.28-10.93%
2 qtrssince 2020-Q2
Decreased
0
EIDXEIDXDelisted

EIDOS THERAPEUTICS INC

2.2M$109.3M2.0%——
8 qtrssince 2018-Q4
Increased
47
ITOSITOSDelisted

ITEOS THERAPEUTICS INC

4.4M$109M2.0%——
1 qtr
New
69
ZGNXZGNXDelisted

ZOGENIX INC

5.5M$98.4M1.8%——
8 qtrssince 2018-Q4
Increased
65
ADVMADVMDelisted

ADVERUM BIOTECHNOLOGIES INC

9.4M$96.9M1.8%———
Increased
56
ADAPYADAPYDelisted
ADR

ADAPTIMMUNE THERAPEUTICS PLC Spon ADS Each Rep 6 Ord Shs

11.3M$90.4M1.7%$3.01+154.84%
3 qtrssince 2020-Q1
Decreased
0
TRILTRILDelisted

Defiance Trillion Dollar Club I

6.2M$87.6M1.6%——
3 qtrssince 2020-Q1
Unchanged
0

ARVINAS INC COM

3.7M$86.7M1.6%$29.09-19.18%
8 qtrssince 2018-Q4
Unchanged
0
$5.5B
AUM
70
Positions
Q3 2020
Filing
HI score · 2.5/5
Quarterly 13F Value Change
-20%Q2'19$1.9B-10%Q3'19$1.7B+96%Q4'19$3.3B-4%Q1'20$3.2B+62%Q2'20$5.1B+7%Q3'20$5.5B
Activity profile
$ moved · Q3'20
New47%Increased17%Decreased30%Exited7%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 2.5 quarters
<1Q24%1-4Q47%1-2Y29%2Y+0%

RA CAPITAL MANAGEMENT, L.P. manages $5.5B across 70 positions as of Q3 2020. Top holdings: ASND (16.7%), FMTX (8.2%), CHEMOCENTRYX INC (4.8%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 2.5/5.0.

Q3 2020 Summary

Active quarter - 18 new positions, 5 exits, 7 increased. Top move: NKTX (NEW, conviction 84). Portfolio: $5.5B across 70 positions.

Top holdings by portfolio weight

Total AUM$5B
ASND16.68%
FMTX8.22%
CHEMOCENTRYX4.84%
PCVX4.77%
TGTX4.32%
NKTX3.08%
AXSM2.65%
PHAT2.57%
MCRB2.46%
NVAX2.38%
Other2.22%

Portfolio allocation by GICS sector

Sectors2
Healthcare67.22%
Unknown32.78%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(2.5 / 5.0)
Holdings P&L31
Conviction41
Concentration91
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
2Q
SLDBSLDBSOLID BIOSCIENCES INC COM NEW
Q1 2026 → Q2 2026+6.2M shares+$87.5M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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