RA CAPITAL MANAGEMENT, L.P.RA CAPITAL MANAGEMENT, L.P.

Institutional investor · Portfolio as of Q4 2020

Top Holdings82 positions

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Activity:
ASNDASND
ADR

ASCENDIS PHARMA A/S

5.9M$978.2M13.7%$83.05+104.93%
9 qtrssince 2018-Q4
Decreased
0

TG Therapeutics Inc

8.7M$451.8M6.3%$8.58+516.13%
9 qtrssince 2018-Q4
Decreased
0

NOVAVAX INC COM NEW

3.8M$422.5M5.9%$107.78+10.38%
3 qtrssince 2020-Q2
Increased
98

NKARTA INC COM

5.6M$344.5M4.8%$30.36+116.37%
2 qtrssince 2020-Q3
Unchanged
0
FMTXFMTXDelisted

FORMA THERAPEUTICS HLDGS INC

9M$314.5M4.4%——
3 qtrssince 2020-Q2
Unchanged
0

ARVINAS INC COM

3.7M$311.9M4.4%$29.09+183.70%
9 qtrssince 2018-Q4
Unchanged
0
4.8M$295.8M4.1%——
5 qtrssince 2019-Q4
Decreased
0

ATEA PHARMACEUTICALS INC COM

5.4M$224.3M3.1%$41.710.00%
1 qtr
New
85
ITOSITOSDelisted

ITEOS THERAPEUTICS INC

4.4M$149.4M2.1%——
2 qtrssince 2020-Q3
Unchanged
0
KNTEKNTEDelisted

KINNATE BIOPHARMA INC

3.6M$142.9M2.0%——
1 qtr
New
69

AXSOME THERAPEUTICS INC

1.7M$134.9M1.9%$50.95+63.40%
8 qtrssince 2019-Q1
Decreased
0

KEROS THERAPEUTICS INC COM

1.9M$132.3M1.8%$38.00-68.55%
3 qtrssince 2020-Q2
Unchanged
0

PHATHOM PHARMACEUTICALS INC

3.8M$127.1M1.8%$32.43+3.86%
5 qtrssince 2019-Q4
Unchanged
0

RHYTHM PHARMACEUTICALS INC

4.2M$124.2M1.7%$23.93+24.22%
9 qtrssince 2018-Q4
Decreased
0

TRAVERE THERAPEUTICS INC COM

4.6M$124.2M1.7%$27.260.00%
1 qtr
New
69

IMMUNOGEN INC

18.4M$118.8M1.7%——
2 qtrssince 2020-Q3
Increased
77

ROCKET PHARMACEUTICALS INC

2.1M$117.1M1.6%$56.050.00%
1 qtr
New
69
ETNBETNBDelisted

89BIO INC

4.7M$115.4M1.6%——
5 qtrssince 2019-Q4
Unchanged
0
ZGNXZGNXDelisted

ZOGENIX INC

5.3M$106.9M1.5%——
9 qtrssince 2018-Q4
Decreased
0

PMV PHARMACEUTICALS INC

1.7M$105.2M1.5%$38.00+48.50%
2 qtrssince 2020-Q3
Unchanged
0
$7.2B
AUM
82
Positions
Q4 2020
Filing
HI score · 2.5/5
Quarterly 13F Value Change
-10%Q3'19$1.7B+96%Q4'19$3.3B-4%Q1'20$3.2B+62%Q2'20$5.1B+7%Q3'20$5.5B+31%Q4'20$7.2B
Activity profile
$ moved · Q4'20
New43%Increased16%Decreased25%Exited15%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 2.5 quarters
<1Q28%1-4Q48%1-2Y11%2Y+13%

RA CAPITAL MANAGEMENT, L.P. manages $7.2B across 82 positions as of Q4 2020. Top holdings: ASND (13.7%), TGTX (6.3%), NVAX (5.9%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 2.5/5.0.

Q4 2020 Summary

Active quarter - 23 new positions, 11 exits, 4 increased. Top move: NVAX (INCREASED, conviction 98). Portfolio: $7.2B across 82 positions.

Top holdings by portfolio weight

Total AUM$7B
ASND13.67%
TGTX6.32%
NVAX5.91%
NKTX4.82%
FMTX4.40%
ARVN4.36%
CHEMOCENTRYX4.13%
AVIR3.14%
ITOS2.09%
KNTE2.00%
Other1.89%

Portfolio allocation by GICS sector

Sectors2
Healthcare71.11%
Unknown28.89%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(2.5 / 5.0)
Holdings P&L29
Conviction41
Concentration91
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
2Q
SLDBSLDBSOLID BIOSCIENCES INC
Q1 2026 → Q2 2026+6.2M shares+$87.5M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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