RA CAPITAL MANAGEMENT, L.P.RA CAPITAL MANAGEMENT, L.P.

Institutional investor · Portfolio as of Q3 2021

SEC EDGAR SourceSEC Filings

Top Holdings95 positions

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Activity:
Stock
Shares
Value
Weight
Avg Buy
Est. P&L
Held
Conviction
ASNDASND
ADR

ASCENDIS PHARMA A/S

7.4M$1.2B16.3%$94.98+65.30%
12 qtrssince 2018-Q4
Increased
67

NOVAVAX INC

2.1M$434.9M6.0%$107.78+88.85%
6 qtrssince 2020-Q2
Decreased
0

CLIMB BIO INC

13.2M$236.5M3.3%$17.230.00%
1 qtr
New
85

INVIVYD INC

5.3M$225.6M3.1%$40.540.00%
1 qtr
New
85
FMTXFMTXDelisted

FORMA THERAPEUTICS HLDGS INC

9M$209M2.9%
6 qtrssince 2020-Q2
Unchanged
0

CYTEK BIOSCIENCES INC

9.6M$205.7M2.9%$20.960.00%
1 qtr
New
79

ATEA PHARMACEUTICALS INC

5.4M$190.3M2.6%$41.61-87.45%
4 qtrssince 2020-Q4
Increased
53

JANUX THERAPEUTICS INC

8.7M$187.5M2.6%$25.37-9.62%
2 qtrssince 2021-Q2
Unchanged
0

Vor Biopharma Inc.

11.1M$174.4M2.4%
8.3M$173.4M2.4%
2 qtrssince 2021-Q2
Unchanged
0
ICVXICVXDelisted

ICOSAVAX INC

5.8M$171M2.4%
1 qtr
New
79
DICEDICEDelisted

DICE THERAPEUTICS INC

5.2M$170.6M2.4%
1 qtr
New
79
7M$169.4M2.3%$18.13+27.37%
3 qtrssince 2021-Q1
Unchanged
0

NKARTA INC

5.6M$155.9M2.2%$30.36-12.15%
5 qtrssince 2020-Q3
Unchanged
0

ACUMEN PHARMACEUTICALS INC

9.8M$145.2M2.0%$14.850.00%
1 qtr
New
78

TG Therapeutics, Inc.

4.1M$136.4M1.9%$13.19+154.50%
12 qtrssince 2018-Q4
Increased
57

TRAVERE THERAPEUTICS INC

5.6M$136.2M1.9%$26.96-11.01%
4 qtrssince 2020-Q4
Unchanged
0

TYRA BIOSCIENCES INC

7.2M$127.3M1.8%$16.910.00%
1 qtr
New
69

MACROGENICS INC

5.9M$124.5M1.7%$28.28-27.54%
6 qtrssince 2020-Q2
Unchanged
0
ITOSITOSDelisted

ITEOS THERAPEUTICS INC

4.4M$119.3M1.7%
5 qtrssince 2020-Q3
Unchanged
0
$7.2B
AUM
95
Positions
Q3 2021
Filing
Rating · 3.0
Quarterly Portfolio Change
+62%Q2'20$5.1B+7%Q3'20$5.5B+31%Q4'20$7.2B-7%Q1'21$6.6B-6%Q2'21$6.2B+16%Q3'21$7.2B
Activity profile
$ moved · Q3'21
New59%Increased15%Decreased8%Exited17%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 3.6 quarters
<1Q20%1-4Q40%1-2Y23%2Y+17%

RA CAPITAL MANAGEMENT, L.P. manages $7.2B across 95 positions as of Q3 2021. Top holdings: ASND (16.3%), NVAX (6.0%), CLYM (3.3%). Fund DNA: Balanced Allocator. HoldingsIntel Rating: 3/5.0.

Q3 2021 Summary

Active quarter - 21 new positions, 18 exits, 8 increased. Top move: CLYM (NEW, conviction 85). Portfolio: $7.2B across 95 positions.

Top holdings by portfolio weight

Total AUM$7B
ASND16.32%
NVAX6.03%
CLYM3.28%
IVVD3.13%
FMTX2.90%
CTKB2.85%
AVIR2.64%
JANX2.60%
VOR2.42%
AEROVATE THE2.40%
Other2.37%

Portfolio allocation by GICS sector

Sectors2
Healthcare78.67%
Unknown21.33%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension quality assessment
Solid(3.0 / 5.0)
Track Record65
Conviction42
Concentration91
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
2Q
SLDBSLDBSOLID BIOSCIENCES INC
Q1 2026 Q2 2026+6.2M shares+$87.5M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

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