RTW INVESTMENTS, LPRTW INVESTMENTS, LP

Institutional investor · Portfolio as of Q3 2019

Top Holdings60 positions

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Activity:

Rocket Pharmaceuticals Inc

16.6M$192.5M11.4%$17.46-32.92%
3 qtrssince 2019-Q1
Unchanged
0

Alnylam Pharmaceuticals Inc

1.8M$142.2M8.5%$80.50+0.74%
3 qtrssince 2019-Q1
Decreased
0

PTC Therapeutics Inc

3.7M$123.5M7.3%$38.47-10.01%
3 qtrssince 2019-Q1
Increased
68
DRNADRNADelisted

Dicerna Pharmaceuticals Inc

6.2M$89.1M5.3%——
3 qtrssince 2019-Q1
Increased
58

Bristol-Myers Squibb Co

1.6M$79.4M4.7%$36.66+7.20%
3 qtrssince 2019-Q1
Increased
54

STOKE THERAPEUTICS INC

3.4M$69.4M4.1%$29.17-29.62%
2 qtrssince 2019-Q2
Unchanged
0

MILESTONE PHARMACEUTICALS IN

3.5M$63.8M3.8%$27.15-30.39%
2 qtrssince 2019-Q2
Unchanged
0

Zimmer Biomet Holdings Inc

403,000$55.3M3.3%$123.820.00%
1 qtr
New
81
MASIMASIDelisted

Masimo Corp

371,155$55.2M3.3%$138.53+5.84%
3 qtrssince 2019-Q1
Decreased
0

Sarepta Therapeutics Inc

724,311$54.6M3.2%$123.90-39.47%
3 qtrssince 2019-Q1
Increased
64
ACHNACHNDelisted

ACHILLION PHARMACEUTICALS IN

13.9M$49.9M3.0%——
3 qtrssince 2019-Q1
Unchanged
0
MRTXMRTXDelisted

Mirati Therapeutics Inc

592,776$46.2M2.7%——
3 qtrssince 2019-Q1
Increased
81
2.4M$44.3M2.6%——
3 qtrssince 2019-Q1
Increased
59
AXNXAXNXDelisted

AXONICS INC

1.5M$41.3M2.5%——
3 qtrssince 2019-Q1
Unchanged
0

Vericel Corp

2.6M$40.1M2.4%$17.53-14.63%
3 qtrssince 2019-Q1
Increased
50

ESTABLISHMENT LABS HLDGS INC

2M$38.6M2.3%$23.06-19.51%
3 qtrssince 2019-Q1
Increased
54
MYOKMYOKDelisted

MYOKARDIA INC

725,025$37.8M2.2%——
3 qtrssince 2019-Q1
Increased
50
ADVMADVMDelisted

Adverum Biotechnologies Inc

6.3M$34.2M2.0%———
Decreased
0
TBIOTBIODelisted

TRANSLATE BIO INC

3.1M$31.2M1.9%——
3 qtrssince 2019-Q1
Increased
57
BLUBLUDelisted

BELLUS Health Inc

4.2M$26.9M1.6%——
1 qtr
New
66
$1.7B
AUM
60
Positions
Q3 2019
Filing
HI score · 3.0/5
Quarterly 13F Value Change
+28%Q2'19$1.9B-10%Q3'19$1.7B
Activity profile
$ moved · Q3'19
New36%Increased30%Decreased18%Exited17%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 1.4 quarters
<1Q25%1-4Q75%1-2Y0%2Y+0%

RTW INVESTMENTS, LP manages $1.7B across 60 positions as of Q3 2019. Top holdings: RCKT (11.4%), ALNY (8.5%), PTCT (7.3%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 3/5.0.

Q3 2019 Summary

Active quarter - 15 new positions, 7 exits, 26 increased. Top move: ZBH (NEW, conviction 81). Portfolio: $1.7B across 60 positions.

Top holdings by portfolio weight

Total AUM$2B
RCKT11.45%
ALNY8.45%
PTCT7.34%
DRNA5.30%
BMY4.72%
STOK4.13%
MIST3.80%
ZBH3.29%
MASI3.28%
SRPT3.24%
Other2.97%

Portfolio allocation by GICS sector

Sectors2
Healthcare76.23%
Unknown23.77%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(3.0 / 5.0)
Holdings P&L53
Conviction44
Concentration72
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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