RTW INVESTMENTS, LPRTW INVESTMENTS, LP

Institutional investor · Portfolio as of Q3 2021

Top Holdings120 positions

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Activity:

ROCKET PHARMACEUTICALS INC

15.8M$469.6M7.1%$18.70+60.16%
11 qtrssince 2019-Q1
Increased
64
SPYSPY
Unit

State Street Spdr S&p 500 Etf Trust TR UNIT

873,255$374.7M5.7%$371.30+10.29%
3 qtrssince 2021-Q1
Decreased
0

ALNYLAM PHARMACEUTICALS INC

1.7M$317.8M4.8%$81.30+118.28%
11 qtrssince 2019-Q1
Unchanged
0
MRTXMRTXDelisted

MIRATI THERAPEUTICS INC

1.5M$264M4.0%——
11 qtrssince 2019-Q1
Increased
58

Thermo Fisher Scientific Inc

416,000$237.7M3.6%$572.960.00%
1 qtr
New
85
MASIMASIDelisted

MASIMO CORP

832,540$225.4M3.4%$193.60+39.68%
11 qtrssince 2019-Q1
Increased
57

Vericel Corporation

4.5M$220.5M3.3%$17.25+179.50%
11 qtrssince 2019-Q1
Unchanged
0

CELLDEX THERAPEUTICS INC NEW COM NEW

3.9M$211M3.2%$14.15+267.19%
6 qtrssince 2020-Q2
Unchanged
0

NATERA INC

1.9M$207.5M3.1%$44.14+152.49%
9 qtrssince 2019-Q3
Increased
61

PTC THERAPEUTICS INC

5.3M$197M3.0%$41.64-11.03%
11 qtrssince 2019-Q1
Unchanged
0

ILLUMINA INC

482,791$195.8M3.0%$334.89+19.56%
5 qtrssince 2020-Q3
Unchanged
0

ESTABLISHMENT LABS HLDGS INC COM

2.3M$166M2.5%$21.90+210.52%
11 qtrssince 2019-Q1
Unchanged
0
DRNADRNADelisted

DICERNA PHARMACEUTICALS INC

7.6M$152.9M2.3%——
11 qtrssince 2019-Q1
Increased
52

TANDEM DIABETES CARE INC

1.2M$138.6M2.1%$80.01+49.88%
7 qtrssince 2020-Q1
Increased
52

Globus Med Inc

1.7M$128M1.9%$64.85+21.66%
4 qtrssince 2020-Q4
Unchanged
0
AXNXAXNXDelisted

AXONICS INC

1.9M$126.5M1.9%——
11 qtrssince 2019-Q1
Unchanged
0
RNAMRNAMDelisted

AVIDITY BIOSCIENCES INC

4.8M$118.1M1.8%$26.39-12.35%
6 qtrssince 2020-Q2
Increased
56

GUARDANT HEALTH INC

925,342$115.7M1.7%$119.32+4.76%
5 qtrssince 2020-Q3
Increased
48

C4 Therapeutics Inc

2.5M$111.5M1.7%$37.61+27.56%
4 qtrssince 2020-Q4
Increased
55
ISEEISEEDelisted

IVERIC BIO INC

6.7M$109.2M1.6%——
6 qtrssince 2020-Q2
Unchanged
0
$6.6B
AUM
120
Positions
Q3 2021
Filing
HI score · 3.0/5
Quarterly 13F Value Change
+53%Q2'20$3.6B+17%Q3'20$4.2B+44%Q4'20$6B+7%Q1'21$6.4B+3%Q2'21$6.6B+0%Q3'21$6.6B
Activity profile
$ moved · Q3'21
New31%Increased40%Decreased19%Exited10%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 1.1 years
<1Q15%1-4Q35%1-2Y22%2Y+28%

RTW INVESTMENTS, LP manages $6.6B across 120 positions as of Q3 2021. Top holdings: RCKT (7.1%), SPY (5.7%), ALNY (4.8%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 3/5.0.

Q3 2021 Summary

Active quarter - 20 new positions, 13 exits, 25 increased. Top move: TMO (NEW, conviction 85). Portfolio: $6.6B across 120 positions.

Top holdings by portfolio weight

Total AUM$7B
RCKT7.08%
SPY5.65%
ALNY4.79%
MRTX3.98%
TMO3.58%
MASI3.40%
VCEL3.32%
CLDX3.18%
NTRA3.13%
PTCT2.97%
Other2.95%

Portfolio allocation by GICS sector

Sectors2
Healthcare73.59%
Unknown26.41%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(3.0 / 5.0)
Holdings P&L51
Conviction44
Concentration72
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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