RTW INVESTMENTS, LPRTW INVESTMENTS, LP

Institutional investor · Portfolio as of Q3 2023

SEC EDGAR SourceSEC Filings

Top Holdings67 positions

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Activity:
Stock
Shares
Value
Weight
Avg Buy
Est. P&L
Held
Conviction

ROCKET PHARMACEUTICALS INC

17.7M$362.4M7.6%$18.79+9.03%
19 qtrssince 2019-Q1
Unchanged
0
IMCRIMCR
ADR

IMMUNOCORE HLDGS PLC

6.1M$316.4M6.7%$43.05+20.55%
11 qtrssince 2021-Q1
Increased
61

AXSOME THERAPEUTICS INC

4.5M$313.8M6.6%$61.42+13.79%
19 qtrssince 2019-Q1
Increased
63

ALNYLAM PHARMACEUTICALS INC

1.7M$298.1M6.3%$94.58+87.25%
19 qtrssince 2019-Q1
Unchanged
0
MRTXMRTXDelisted

MIRATI THERAPEUTICS INC

6.8M$294.8M6.2%
19 qtrssince 2019-Q1
Increased
83
ARGXARGX
ADR

ARGENX SE - ADR

507,195$249.4M5.3%$338.40+45.28%
19 qtrssince 2019-Q1
Increased
63

ACADIA Pharmaceuticals Inc.

11.6M$241.3M5.1%$18.32+13.78%
6 qtrssince 2022-Q2
Increased
70

BRUKER CORP

3.4M$210.7M4.4%$72.62-14.96%
3 qtrssince 2023-Q1
Increased
64

Ultragenyx Pharmaceutical, Inc.

5.4M$192.7M4.1%$54.54-34.64%
8 qtrssince 2021-Q4
Unchanged
0

PENUMBRA INC

673,371$162.9M3.4%$262.94-8.00%
9 qtrssince 2021-Q3
Unchanged
0

PTC THERAPEUTICS INC

7.2M$162.1M3.4%$43.80-48.84%
19 qtrssince 2019-Q1
Unchanged
0

THERMO FISHER SCIENTIFIC INC

290,334$147M3.1%$570.15-11.83%
9 qtrssince 2021-Q3
Unchanged
0
MASIMASIDelisted

MASIMO CORP

1.5M$131.7M2.8%$174.28-49.69%
19 qtrssince 2019-Q1
Unchanged
0

ESTABLISHMENT LABS HLDGS INC

2.5M$122.4M2.6%$24.97+96.52%
19 qtrssince 2019-Q1
Unchanged
0

NATERA INC

2.7M$117.3M2.5%$42.12+5.07%
17 qtrssince 2019-Q3
Increased
52

VERICEL CORP

3.3M$110.3M2.3%$17.89+87.41%
19 qtrssince 2019-Q1
Unchanged
0

SAGE THERAPEUTICS INC

5.1M$106M2.2%
1 qtr
New
78

Celldex Therapeutics, Inc.

3.5M$95.3M2.0%$16.46+67.20%
14 qtrssince 2020-Q2
Unchanged
0

PROTAGONIST THERAPEUTICS INC

5.4M$90.3M1.9%$22.38-25.48%
17 qtrssince 2019-Q3
Unchanged
0

CYTOKINETICS INC

2.6M$75.8M1.6%$27.00+9.10%
13 qtrssince 2020-Q3
Unchanged
0
$4.7B
AUM
67
Positions
Q3 2023
Filing
Rating · 3.0
Quarterly Portfolio Change
-20%Q2'22$3.9B+12%Q3'22$4.3B+13%Q4'22$4.9B-2%Q1'23$4.8B+9%Q2'23$5.3B-10%Q3'23$4.7B
Activity profile
$ moved · Q3'23
New29%Increased41%Decreased10%Exited20%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 2.3 years
<1Q15%1-4Q15%1-2Y9%2Y+61%

RTW INVESTMENTS, LP manages $4.7B across 67 positions as of Q3 2023. Top holdings: RCKT (7.6%), IMCR (6.7%), AXSM (6.6%). Fund DNA: Balanced Allocator. HoldingsIntel Rating: 3/5.0.

Q3 2023 Summary

Active quarter - 10 new positions, 5 exits, 16 increased. Top move: MRTX (INCREASED, conviction 83). Portfolio: $4.7B across 67 positions.

Top holdings by portfolio weight

Total AUM$5B
RCKT7.65%
IMCR6.68%
AXSM6.62%
ALNY6.29%
MRTX6.22%
ARGX5.26%
ACAD5.09%
BRKR4.45%
RARE4.07%
PEN3.44%
Other3.42%

Portfolio allocation by GICS sector

Sectors2
Healthcare87.64%
Unknown12.36%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension quality assessment
Solid(3.0 / 5.0)
Track Record36
Conviction45
Concentration72
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

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