RTW INVESTMENTS, LPRTW INVESTMENTS, LP

Institutional investor · Portfolio as of Q4 2020

Top Holdings102 positions

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Activity:

ROCKET PHARMACEUTICALS INC

17.1M$935.6M15.7%$18.09+209.82%
8 qtrssince 2019-Q1
Increased
63

IMMUNOVANT INC

7.6M$350.7M5.9%$22.69+117.45%
5 qtrssince 2019-Q4
Increased
61

PTC THERAPEUTICS INC

4.2M$257.7M4.3%$40.33+51.45%
8 qtrssince 2019-Q1
Increased
60
MRTXMRTXDelisted

MIRATI THERAPEUTICS INC

1.1M$231.6M3.9%——
8 qtrssince 2019-Q1
Decreased
0

STOKE THERAPEUTICS INC

3.5M$219.5M3.7%$29.08+106.54%
7 qtrssince 2019-Q2
Unchanged
0

ALNYLAM PHARMACEUTICALS INC

1.7M$218.6M3.7%$81.24+61.30%
8 qtrssince 2019-Q1
Unchanged
0

NATERA INC

1.7M$170.4M2.9%$38.24+160.26%
6 qtrssince 2019-Q3
Increased
52
DRNADRNADelisted

DICERNA PHARMACEUTICALS INC

7.3M$159.8M2.7%——
8 qtrssince 2019-Q1
Increased
52

ARVINAS INC

1.8M$152.1M2.6%$82.530.00%
1 qtr
New
78

VERICEL CORP

4.5M$139.5M2.3%$17.25+82.66%
8 qtrssince 2019-Q1
Increased
60

AXSOME THERAPEUTICS INC

1.7M$136.3M2.3%$49.30+68.89%
8 qtrssince 2019-Q1
Increased
52

ILLUMINA INC

361,778$133.9M2.2%$326.60+8.44%
2 qtrssince 2020-Q3
Increased
84

CERNER CORP

1.7M$133.5M2.2%——
3 qtrssince 2020-Q2
Increased
62
MASIMASIDelisted

MASIMO CORP

469,416$126M2.1%$157.61+69.73%
8 qtrssince 2019-Q1
Increased
54

GLOBUS MED INC

1.6M$107M1.8%$64.920.00%
1 qtr
New
69
RNAMRNAMDelisted

AVIDITY BIOSCIENCES INC

4M$102M1.7%$27.04-1.63%
3 qtrssince 2020-Q2
Unchanged
0

TARSUS PHARMACEUTICALS INC

2.5M$99M1.7%$41.920.00%
1 qtr
New
68
AXNXAXNXDelisted

AXONICS INC

1.9M$94M1.6%——
8 qtrssince 2019-Q1
Unchanged
0
DMTKQDMTKQDelisted

DERMTECH INC

2.9M$93.7M1.6%——
6 qtrssince 2019-Q3
Unchanged
0

10X GENOMICS INC

660,933$93.6M1.6%$79.79+78.73%
6 qtrssince 2019-Q3
Unchanged
0
$6B
AUM
102
Positions
Q4 2020
Filing
HI score · 3.5/5
Quarterly 13F Value Change
-10%Q3'19$1.7B+58%Q4'19$2.7B-12%Q1'20$2.3B+53%Q2'20$3.6B+17%Q3'20$4.2B+44%Q4'20$6B
Activity profile
$ moved · Q4'20
New30%Increased50%Decreased4%Exited16%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 3.2 quarters
<1Q25%1-4Q30%1-2Y45%2Y+0%

RTW INVESTMENTS, LP manages $6B across 102 positions as of Q4 2020. Top holdings: RCKT (15.7%), IMVT (5.9%), PTCT (4.3%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 3.5/5.0.

Q4 2020 Summary

Active quarter - 26 new positions, 14 exits, 35 increased. Top move: ILMN (INCREASED, conviction 84). Portfolio: $6.0B across 102 positions.

Top holdings by portfolio weight

Total AUM$6B
RCKT15.70%
IMVT5.88%
PTCT4.32%
MRTX3.89%
STOK3.68%
ALNY3.67%
NTRA2.86%
DRNA2.68%
ARVN2.55%
VCEL2.34%
Other2.29%

Portfolio allocation by GICS sector

Sectors2
Healthcare78.34%
Unknown21.66%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Strong(3.5 / 5.0)
Holdings P&L53
Conviction44
Concentration72
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

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Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

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6Q
IMTXIMTXIMMATICS N.V
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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