RTW INVESTMENTS, LP
Institutional investor · Portfolio as of Q4 2022
Top Holdings77 positions
Stock | Shares | Value | Weight | Avg Buy | Est. P&L | Held | Conviction |
|---|---|---|---|---|---|---|---|
ALNYLAM PHARMACEUTICALS INC | 1.7M | $400.1M | 8.2% | $94.58 | +151.27% | 16 qtrssince 2019-Q1 | Unchanged 0 |
PROMETHEUS BIOSCIENCES INC | 3.4M | $369M | 7.5% | — | — | 8 qtrssince 2021-Q1 | Increased 64 |
ROCKET PHARMACEUTICALS INC | 17.7M | $346.1M | 7.1% | $18.79 | +4.13% | 16 qtrssince 2019-Q1 | Increased 67 |
IMMUNOCORE HLDGS PLC | 5.6M | $317.3M | 6.5% | $41.88 | +36.26% | 8 qtrssince 2021-Q1 | Increased 74 |
THERMO FISHER SCIENTIFIC INC | 435,500 | $239.8M | 4.9% | $570.15 | -4.27% | 6 qtrssince 2021-Q3 | Unchanged 0 |
AXSOME THERAPEUTICS INC | 3M | $229.9M | 4.7% | $59.09 | +30.53% | 16 qtrssince 2019-Q1 | Increased 80 |
MASIMO CORP | 1.5M | $222.1M | 4.5% | $174.28 | -15.11% | 16 qtrssince 2019-Q1 | Increased 59 |
PTC THERAPEUTICS INC | 5.6M | $214.3M | 4.4% | $42.53 | -10.26% | 16 qtrssince 2019-Q1 | Decreased 0 |
Ultragenyx Pharmaceutical, Inc. | 4M | $183.8M | 3.8% | $58.02 | -20.15% | 5 qtrssince 2021-Q4 | Increased 83 |
ARGENX SE - ADR | 482,195 | $182.7M | 3.7% | $328.92 | +15.18% | 16 qtrssince 2019-Q1 | Increased 58 |
MIRATI THERAPEUTICS INC | 3.6M | $165.1M | 3.4% | — | — | 16 qtrssince 2019-Q1 | Increased 89 |
ESTABLISHMENT LABS HLDGS INC | 2.4M | $155.9M | 3.2% | $22.72 | +188.93% | 16 qtrssince 2019-Q1 | Increased 56 |
PENUMBRA INC | 698,371 | $155.4M | 3.2% | $262.94 | -15.39% | 6 qtrssince 2021-Q3 | Unchanged 0 |
Celldex Therapeutics, Inc. | 3.1M | $137.5M | 2.8% | $14.23 | +213.14% | 11 qtrssince 2020-Q2 | Unchanged 0 |
| 5.6M | $124.4M | 2.5% | $25.41 | -12.69% | 11 qtrssince 2020-Q2 | Increased 56 | |
CYTOKINETICS INC | 2.6M | $117.9M | 2.4% | $27.00 | +69.69% | 10 qtrssince 2020-Q3 | Unchanged 0 |
ILLUMINA INC | 564,375 | $114.1M | 2.3% | $320.70 | -38.67% | 10 qtrssince 2020-Q3 | Unchanged 0 |
NATERA INC | 2.6M | $104.8M | 2.1% | $42.07 | -4.52% | 14 qtrssince 2019-Q3 | Increased 60 |
VERICEL CORP | 3.1M | $81.7M | 1.7% | $17.25 | +52.74% | 16 qtrssince 2019-Q1 | Unchanged 0 |
CUTERA INC | 1.8M | $79.5M | 1.6% | — | — | 7 qtrssince 2021-Q2 | Increased 48 |
RTW INVESTMENTS, LP manages $4.9B across 77 positions as of Q4 2022. Top holdings: ALNY (8.2%), RXDX (7.5%), RCKT (7.1%). Fund DNA: Diversified Scout. HoldingsIntel Rating: 3/5.0.
Active quarter - 1 new positions, 10 exits, 20 increased. Top move: MRTX (INCREASED, conviction 89). Portfolio: $4.9B across 77 positions.
Top holdings by portfolio weight
Portfolio allocation by GICS sector
Behavioral investing profile
Position Outcomes
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Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer