RTW INVESTMENTS, LPRTW INVESTMENTS, LP

Institutional investor · Portfolio as of Q2 2021

Top Holdings113 positions

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Activity:

Rocket Pharmaceuticals Inc

15M$663.9M10.0%$18.09+139.51%
10 qtrssince 2019-Q1
Decreased
0
SPYSPY
Unit

SPDR S&P 500 ETF Trust

996,255$426.5M6.4%$371.30+8.23%
2 qtrssince 2021-Q1
Increased
64

Alnylam Pharmaceuticals Inc

1.7M$285.4M4.3%$81.30+104.03%
10 qtrssince 2019-Q1
Unchanged
0
DRNADRNADelisted

Dicerna Pharmaceuticals Inc

7.5M$280.7M4.2%——
10 qtrssince 2019-Q1
Increased
57

Vericel Corp

4.5M$237.2M3.6%$17.25+234.99%
10 qtrssince 2019-Q1
Unchanged
0
MRTXMRTXDelisted

Mirati Therapeutics Inc

1.5M$235.4M3.6%——
10 qtrssince 2019-Q1
Increased
62

Illumina Inc

482,791$228.5M3.4%$334.89+39.19%
4 qtrssince 2020-Q3
Increased
56

PTC Therapeutics Inc

5.3M$223.8M3.4%$41.64+0.91%
10 qtrssince 2019-Q1
Unchanged
0

ESTABLISHMENT LABS HLDGS INC

2.3M$202.6M3.1%$21.90+295.58%
10 qtrssince 2019-Q1
Unchanged
0
MASIMASIDelisted

Masimo Corp

826,210$200.3M3.0%$193.01+27.91%
10 qtrssince 2019-Q1
Increased
74

NATERA INC

1.7M$194.4M2.9%$38.24+196.89%
8 qtrssince 2019-Q3
Unchanged
0

PROTAGONIST THERAPEUTICS INC

3.5M$157.4M2.4%$11.14+302.81%
8 qtrssince 2019-Q3
Unchanged
0

10X Genomics Inc

734,481$143.8M2.2%$89.68+124.49%
8 qtrssince 2019-Q3
Increased
54

CELLDEX THERAPEUTICS INC NEW

3.9M$130.7M2.0%$14.15+149.90%
5 qtrssince 2020-Q2
Unchanged
0
DMTKQDMTKQDelisted

DERMTECH INC

3.1M$129.6M2.0%——
8 qtrssince 2019-Q3
Unchanged
0

GLOBUS MED INC

1.7M$129.5M2.0%$64.85+17.75%
3 qtrssince 2020-Q4
Unchanged
0
AXNXAXNXDelisted

AXONICS INC

1.9M$123.3M1.9%——
10 qtrssince 2019-Q1
Increased
49

STOKE THERAPEUTICS INC

3.6M$122.7M1.9%$29.30+12.65%
9 qtrssince 2019-Q2
Unchanged
0

GUARDANT HEALTH INC

918,253$114M1.7%$119.28+4.12%
4 qtrssince 2020-Q3
Increased
66

Quidel Corp

878,533$112.6M1.7%$126.39-89.38%
2 qtrssince 2021-Q1
Unchanged
0
$6.6B
AUM
113
Positions
Q2 2021
Filing
HI score · 3.5/5
Quarterly 13F Value Change
-12%Q1'20$2.3B+53%Q2'20$3.6B+17%Q3'20$4.2B+44%Q4'20$6B+7%Q1'21$6.4B+3%Q2'21$6.6B
Activity profile
$ moved · Q2'21
New12%Increased40%Decreased13%Exited35%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 1.0 years
<1Q12%1-4Q41%1-2Y25%2Y+22%

RTW INVESTMENTS, LP manages $6.6B across 113 positions as of Q2 2021. Top holdings: RCKT (10.0%), SPY (6.4%), ALNY (4.3%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 3.5/5.0.

Q2 2021 Summary

Active quarter - 15 new positions, 13 exits, 21 increased. Top move: MASI (INCREASED, conviction 74). Portfolio: $6.6B across 113 positions.

Top holdings by portfolio weight

Total AUM$7B
RCKT10.02%
SPY6.44%
ALNY4.31%
DRNA4.24%
VCEL3.58%
MRTX3.55%
ILMN3.45%
PTCT3.38%
ESTA3.06%
MASI3.02%
Other2.93%

Portfolio allocation by GICS sector

Sectors2
Healthcare71.34%
Unknown28.66%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Strong(3.5 / 5.0)
Holdings P&L53
Conviction44
Concentration72
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

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Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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