RTW INVESTMENTS, LPRTW INVESTMENTS, LP

Institutional investor · Portfolio as of Q4 2019

Top Holdings61 positions

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Activity:

ROCKET PHARMACEUTICALS INC

16.8M$382.7M14.4%$17.53+31.88%
4 qtrssince 2019-Q1
Increased
61

ALNYLAM PHARMACEUTICALS INC

1.6M$188.6M7.1%$80.50+42.47%
4 qtrssince 2019-Q1
Decreased
0

PTC THERAPEUTICS INC

3.8M$184.1M6.9%$38.90+22.24%
4 qtrssince 2019-Q1
Increased
62
DRNADRNADelisted

DICERNA PHARMACEUTICALS INC

5.9M$129.4M4.9%——
4 qtrssince 2019-Q1
Decreased
0

AXSOME THERAPEUTICS INC

1M$106.1M4.0%$32.80+216.55%
4 qtrssince 2019-Q1
Increased
66

BRISTOL MYERS SQUIBBCO

1.6M$105.5M4.0%$37.30+34.81%
4 qtrssince 2019-Q1
Increased
58

STOKE THERAPEUTICS INC

3.5M$100.4M3.8%$29.08-5.24%
3 qtrssince 2019-Q2
Increased
58
4.3M$90M3.4%——
4 qtrssince 2019-Q1
Increased
83
MRTXMRTXDelisted

MIRATI THERAPEUTICS INC

645,427$83.2M3.1%——
4 qtrssince 2019-Q1
Increased
60

SAREPTA THERAPEUTICS INC

605,762$78.2M2.9%$123.90+3.95%
4 qtrssince 2019-Q1
Decreased
0
ADVMADVMDelisted

ADVERUM BIOTECHNOLOGIES INC

6.4M$73.6M2.8%$54.05+107.60%
4 qtrssince 2019-Q1
Increased
52

IMMUNOVANT INC

4.4M$66M2.5%$15.810.00%
1 qtr
New
76

ZIMMER BIOMET HOLDINGS INC

437,385$65.5M2.5%$124.90+10.11%
2 qtrssince 2019-Q3
Increased
55

MILESTONE PHARMACEUTICALS IN

4M$63.4M2.4%$25.87-39.97%
3 qtrssince 2019-Q2
Increased
57
MASIMASIDelisted

MASIMO CORP

382,187$60.4M2.3%$139.11+14.01%
4 qtrssince 2019-Q1
Increased
52

ESTABLISHMENT LABS HLDGS INC

2M$56.2M2.1%$23.06+17.74%
4 qtrssince 2019-Q1
Decreased
0
MYOKMYOKDelisted

MYOKARDIA INC

760,988$55.5M2.1%——
4 qtrssince 2019-Q1
Increased
53

VERICEL CORP

3M$52M2.0%$17.50-1.44%
4 qtrssince 2019-Q1
Increased
52

PROQR THRAPEUTICS N V

4.8M$47.4M1.8%$12.87-26.59%
4 qtrssince 2019-Q1
Increased
58
AXNXAXNXDelisted

AXONICS INC

1.6M$44.1M1.7%——
4 qtrssince 2019-Q1
Increased
48
$2.7B
AUM
61
Positions
Q4 2019
Filing
HI score · 3.5/5
Quarterly 13F Value Change
+28%Q2'19$1.9B-10%Q3'19$1.7B+58%Q4'19$2.7B
Activity profile
$ moved · Q4'19
New19%Increased60%Decreased16%Exited6%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 2.0 quarters
<1Q18%1-4Q82%1-2Y0%2Y+0%

RTW INVESTMENTS, LP manages $2.7B across 61 positions as of Q4 2019. Top holdings: RCKT (14.4%), ALNY (7.1%), PTCT (6.9%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 3.5/5.0.

Q4 2019 Summary

Active quarter - 13 new positions, 12 exits, 31 increased. Top move: IMVT (NEW, conviction 76). Portfolio: $2.7B across 61 positions.

Top holdings by portfolio weight

Total AUM$3B
RCKT14.44%
ALNY7.12%
PTCT6.95%
DRNA4.88%
AXSM4.00%
BMY3.98%
STOK3.79%
HOMOLOGY MED3.40%
MRTX3.14%
SRPT2.95%
Other2.78%

Portfolio allocation by GICS sector

Sectors2
Healthcare77.70%
Unknown22.30%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Strong(3.5 / 5.0)
Holdings P&L53
Conviction44
Concentration72
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

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Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

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6Q
IMTXIMTXIMMATICS N.V SHS
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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