RTW INVESTMENTS, LP
Institutional investor · Portfolio as of Q3 2022
Top Holdings86 positions
Stock | Shares | Value | Weight | Avg Buy | Est. P&L | Held | Conviction |
|---|---|---|---|---|---|---|---|
ALNYLAM PHARMACEUTICALS INC | 1.7M | $336.9M | 7.8% | $94.58 | +121.39% | 15 qtrssince 2019-Q1 | Unchanged 0 |
PTC THERAPEUTICS INC | 5.6M | $282.2M | 6.5% | $42.53 | +18.38% | 15 qtrssince 2019-Q1 | Increased 67 |
ROCKET PHARMACEUTICALS INC | 15.8M | $252.2M | 5.8% | $18.70 | -24.92% | 15 qtrssince 2019-Q1 | Unchanged 0 |
THERMO FISHER SCIENTIFIC INC | 435,500 | $220.9M | 5.1% | $570.15 | -10.24% | 5 qtrssince 2021-Q3 | Unchanged 0 |
IMMUNOCORE HLDGS PLC | 4.5M | $209M | 4.8% | $38.10 | +20.30% | 7 qtrssince 2021-Q1 | Increased 63 |
MASIMO CORP | 1.4M | $203.3M | 4.7% | $175.41 | -18.81% | 15 qtrssince 2019-Q1 | Increased 60 |
PROMETHEUS BIOSCIENCES INC | 3.2M | $188.2M | 4.3% | — | — | 7 qtrssince 2021-Q1 | Unchanged 0 |
ARGENX SE - ADR | 467,195 | $164.9M | 3.8% | $327.31 | +9.24% | 15 qtrssince 2019-Q1 | Increased 59 |
PENUMBRA INC | 698,371 | $132.4M | 3.1% | $262.94 | -27.05% | 5 qtrssince 2021-Q3 | Unchanged 0 |
MIRATI THERAPEUTICS INC | 1.9M | $131.5M | 3.0% | — | — | 15 qtrssince 2019-Q1 | Unchanged 0 |
ESTABLISHMENT LABS HLDGS INC | 2.4M | $129.4M | 3.0% | $22.63 | +133.75% | 15 qtrssince 2019-Q1 | Unchanged 0 |
CYTOKINETICS INC | 2.6M | $124.7M | 2.9% | $27.00 | +79.43% | 9 qtrssince 2020-Q3 | Increased 52 |
ILLUMINA INC | 564,375 | $107.7M | 2.5% | $320.70 | -41.21% | 9 qtrssince 2020-Q3 | Unchanged 0 |
RELMADA THERAPEUTICS INC | 2.6M | $97.9M | 2.3% | $32.16 | +12.54% | 12 qtrssince 2019-Q4 | Increased 51 |
Ultragenyx Pharmaceutical, Inc. | 2.4M | $97.7M | 2.3% | $65.98 | -38.54% | 4 qtrssince 2021-Q4 | Increased 77 |
NATERA INC | 2.2M | $96.8M | 2.2% | $42.42 | +4.84% | 13 qtrssince 2019-Q3 | Increased 53 |
Celldex Therapeutics, Inc. | 3.1M | $86.7M | 2.0% | $14.23 | +99.18% | 10 qtrssince 2020-Q2 | Unchanged 0 |
| 5.2M | $84.4M | 1.9% | $25.69 | -34.90% | 10 qtrssince 2020-Q2 | Increased 51 | |
AXSOME THERAPEUTICS INC | 1.9M | $84M | 1.9% | $48.56 | -9.09% | 15 qtrssince 2019-Q1 | Increased 54 |
CUTERA INC | 1.8M | $80.7M | 1.9% | — | — | 6 qtrssince 2021-Q2 | Unchanged 0 |
RTW INVESTMENTS, LP manages $4.3B across 86 positions as of Q3 2022. Top holdings: ALNY (7.8%), PTCT (6.5%), RCKT (5.8%). Fund DNA: Diversified Scout. HoldingsIntel Rating: 3/5.0.
Active quarter - 4 new positions, 25 exits, 17 increased. Top move: RARE (INCREASED, conviction 77). Portfolio: $4.3B across 86 positions.
Top holdings by portfolio weight
Portfolio allocation by GICS sector
Behavioral investing profile
Position Outcomes
Best and worst performing positions by estimated return
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Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer