RTW INVESTMENTS, LPRTW INVESTMENTS, LP

Institutional investor · Portfolio as of Q2 2023

Top Holdings62 positions

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Activity:
IMCRIMCR
ADR

IMMUNOCORE HLDGS PLC ADS

6M$361.5M6.9%$42.95+33.91%
10 qtrssince 2021-Q1
Increased
65

ROCKET PHARMACEUTICALS INC

17.7M$351.5M6.7%$18.79+6.69%
18 qtrssince 2019-Q1
Unchanged
0

ALNYLAM PHARMACEUTICALS INC

1.7M$319.7M6.1%$94.58+102.01%
18 qtrssince 2019-Q1
Unchanged
0

AXSOME THERAPEUTICS INC

4.3M$307.9M5.9%$61.01+19.85%
18 qtrssince 2019-Q1
Increased
68

PTC THERAPEUTICS INC

7.2M$294.3M5.6%$43.80-5.87%
18 qtrssince 2019-Q1
Increased
61

ULTRAGENYX PHARMACEUTICAL INC COM

5.4M$249.3M4.7%$54.63-15.56%
7 qtrssince 2021-Q4
Increased
70
MASIMASIDelisted

MASIMO CORP

1.5M$247.1M4.7%$174.28-4.97%
18 qtrssince 2019-Q1
Unchanged
0

ACADIA PHARMACEUTICALS INC

9.8M$234.3M4.5%$17.85+34.15%
5 qtrssince 2022-Q2
Increased
66

Penumbra Inc.

673,371$231.7M4.4%$262.94+29.45%
8 qtrssince 2021-Q3
Unchanged
0

BRUKER CORP

3M$218.8M4.2%$74.17-2.48%
2 qtrssince 2023-Q1
Increased
91
ARGXARGX
ADR

ARGENX SE

482,195$187.9M3.6%$330.45+17.94%
18 qtrssince 2019-Q1
Unchanged
0

ESTABLISHMENT LABS HLDGS INC COM

2.5M$171.1M3.3%$24.97+179.06%
18 qtrssince 2019-Q1
Increased
58
MRTXMRTXDelisted

MIRATI THERAPEUTICS INC

4.5M$161.6M3.1%——
18 qtrssince 2019-Q1
Increased
67

Thermo Fisher Scientific Inc

290,334$151.5M2.9%$570.15-10.46%
8 qtrssince 2021-Q3
Unchanged
0

PROTAGONIST THERAPEUTICS INC COM

5.4M$149.6M2.8%$22.38+23.62%
16 qtrssince 2019-Q3
Increased
61

NATERA INC

2.6M$127.1M2.4%$42.77+13.76%
16 qtrssince 2019-Q3
Unchanged
0

Vericel Corporation

3.3M$123.7M2.4%$17.89+114.53%
18 qtrssince 2019-Q1
Unchanged
0

CELLDEX THERAPEUTICS INC NEW COM NEW

3.5M$117.5M2.2%$16.46+110.09%
13 qtrssince 2020-Q2
Increased
58
6.8M$112.2M2.1%——
15 qtrssince 2019-Q4
Increased
61

HORIZON THERAPEUTICS PUB L

1M$102.9M2.0%——
1 qtr
New
68
$5.3B
AUM
62
Positions
Q2 2023
Filing
HI score · 3.0/5
Quarterly 13F Value Change
-29%Q1'22$4.8B-20%Q2'22$3.9B+12%Q3'22$4.3B+13%Q4'22$4.9B-2%Q1'23$4.8B+9%Q2'23$5.3B
Activity profile
$ moved · Q2'23
New21%Increased51%Decreased0%Exited28%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 2.3 years
<1Q13%1-4Q10%1-2Y13%2Y+65%

RTW INVESTMENTS, LP manages $5.3B across 62 positions as of Q2 2023. Top holdings: IMCR (6.9%), RCKT (6.7%), ALNY (6.1%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 3/5.0.

Q2 2023 Summary

Active quarter - 10 new positions, 8 exits, 19 increased. Top move: BRKR (INCREASED, conviction 91). Portfolio: $5.3B across 62 positions.

Top holdings by portfolio weight

Total AUM$5B
IMCR6.88%
RCKT6.69%
ALNY6.09%
AXSM5.86%
PTCT5.60%
RARE4.75%
MASI4.70%
ACAD4.46%
PEN4.41%
BRKR4.16%
Other3.58%

Portfolio allocation by GICS sector

Sectors2
Healthcare89.76%
Unknown10.24%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(3.0 / 5.0)
Holdings P&L51
Conviction44
Concentration72
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

Funds with similar investing DNA

Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

Security
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6Q
CMPSCMPSCOMPASS PATHWAYS PLC
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6Q
IMTXIMTXIMMATICS N.V
Q1 2025 → Q2 2026+6.4M shares+$84.6M
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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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