RTW INVESTMENTS, LPRTW INVESTMENTS, LP

Institutional investor · Portfolio as of Q3 2020

Top Holdings90 positions

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Activity:

Rocket Pharmaceuticals Inc

16.8M$384.3M9.3%$17.53+31.71%
7 qtrssince 2019-Q1
Unchanged
0

IMMUNOVANT INC

7.5M$264.3M6.4%$22.40+62.76%
4 qtrssince 2019-Q4
Increased
76

Alnylam Pharmaceuticals Inc

1.7M$244.8M5.9%$81.24+78.49%
7 qtrssince 2019-Q1
Unchanged
0

PTC Therapeutics Inc

4M$186.7M4.5%$39.14+20.76%
7 qtrssince 2019-Q1
Increased
56
MRTXMRTXDelisted

Mirati Therapeutics Inc

1.1M$182M4.4%——
7 qtrssince 2019-Q1
Increased
56
DRNADRNADelisted

Dicerna Pharmaceuticals Inc

7.2M$130M3.1%——
7 qtrssince 2019-Q1
Increased
56
MYOKMYOKDelisted

MYOKARDIA INC

936,931$127.7M3.1%——
7 qtrssince 2019-Q1
Unchanged
0

NATERA INC

1.7M$123.6M3.0%$38.19+89.17%
5 qtrssince 2019-Q3
Increased
58

AXSOME THERAPEUTICS INC

1.7M$119.1M2.9%$49.27+46.71%
7 qtrssince 2019-Q1
Increased
52

STOKE THERAPEUTICS INC

3.5M$118.7M2.9%$29.08+18.04%
6 qtrssince 2019-Q2
Unchanged
0
RNAMRNAMDelisted

AVIDITY BIOSCIENCES INC

4M$109.9M2.6%$27.04+6.84%
2 qtrssince 2020-Q2
Unchanged
0
MASIMASIDelisted

Masimo Corp

450,390$106.3M2.6%$152.97+51.87%
7 qtrssince 2019-Q1
Increased
59

Cerner Corp

1.4M$100.6M2.4%——
2 qtrssince 2020-Q2
Increased
60
AXNXAXNXDelisted

AXONICS INC

1.9M$96.2M2.3%——
7 qtrssince 2019-Q1
Increased
51

Baxter International Inc

1.1M$86.6M2.1%$74.80-67.45%
2 qtrssince 2020-Q2
Increased
57

10X Genomics Inc

660,933$82.4M2.0%$79.79+56.62%
5 qtrssince 2019-Q3
Increased
49
ADVMADVMDelisted

Adverum Biotechnologies Inc

7.2M$74.5M1.8%———
Increased
50

Vericel Corp

3.9M$71.4M1.7%$14.78+23.09%
7 qtrssince 2019-Q1
Increased
46

Tandem Diabetes Care Inc

603,481$68.5M1.6%$73.45+53.32%
3 qtrssince 2020-Q1
Increased
47

PROTAGONIST THERAPEUTICS INC

3.4M$66.6M1.6%$10.50+86.12%
5 qtrssince 2019-Q3
Increased
47
$4.2B
AUM
90
Positions
Q3 2020
Filing
HI score · 3.0/5
Quarterly 13F Value Change
+28%Q2'19$1.9B-10%Q3'19$1.7B+58%Q4'19$2.7B-12%Q1'20$2.3B+53%Q2'20$3.6B+17%Q3'20$4.2B
Activity profile
$ moved · Q3'20
New36%Increased50%Decreased9%Exited6%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 3.0 quarters
<1Q23%1-4Q31%1-2Y46%2Y+0%

RTW INVESTMENTS, LP manages $4.2B across 90 positions as of Q3 2020. Top holdings: RCKT (9.3%), IMVT (6.4%), ALNY (5.9%). Fund DNA: Balanced Allocator. HoldingsIntel Score: 3/5.0.

Q3 2020 Summary

Active quarter - 22 new positions, 9 exits, 37 increased. Top move: IMVT (INCREASED, conviction 76). Portfolio: $4.2B across 90 positions.

Top holdings by portfolio weight

Total AUM$4B
RCKT9.25%
IMVT6.36%
ALNY5.90%
PTCT4.49%
MRTX4.38%
DRNA3.13%
MYOK3.08%
NTRA2.98%
AXSM2.87%
STOK2.86%
Other2.65%

Portfolio allocation by GICS sector

Sectors2
Healthcare73.12%
Unknown26.88%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare, Unknown
Compare DNA across all funds
7-dimension, SEC 13F-derived research score
Solid(3.0 / 5.0)
Holdings P&L53
Conviction44
Concentration72
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

Similar Funds

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Accumulation Streaks

Positions with 2+ consecutive quarters of increases - persistent directional conviction.

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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

Verify source filings on SEC EDGAR

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