RTW INVESTMENTS, LPRTW INVESTMENTS, LP

Institutional investor · Portfolio as of Q3 2024

SEC EDGAR SourceSEC Filings

Top Holdings68 positions

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Activity:
Stock
Shares
Value
Weight
Avg Buy
Est. P&L
Held
Conviction

MADRIGAL PHARMACEUTICALS INC

2M$423.1M6.1%$265.36-19.95%
6 qtrssince 2023-Q2
Increased
63

AXSOME THERAPEUTICS INC

4.2M$376.5M5.4%$62.01+44.55%
23 qtrssince 2019-Q1
Decreased
0
8.1M$373.5M5.4%$25.64+65.10%
18 qtrssince 2020-Q2
Decreased
0
ARGXARGX
ADR

ARGENX SE - ADR

654,430$354.8M5.1%$348.48+55.56%
23 qtrssince 2019-Q1
Unchanged
0

NATERA INC

2.6M$329.2M4.8%$42.12+198.51%
21 qtrssince 2019-Q3
Unchanged
0

ROCKET PHARMACEUTICALS INC

17.7M$326.7M4.7%$18.79-1.77%
23 qtrssince 2019-Q1
Unchanged
0

PTC THERAPEUTICS INC

7.4M$274.3M4.0%$43.39-13.43%
23 qtrssince 2019-Q1
Unchanged
0

DYNE THERAPEUTICS INC

6.8M$244.9M3.5%$32.07+5.49%
3 qtrssince 2024-Q1
Increased
60

PROTAGONIST THERAPEUTICS INC

5.4M$244.2M3.5%$22.95+94.12%
21 qtrssince 2019-Q3
Increased
58

BRUKER CORP

3.5M$240.4M3.5%$72.33-2.86%
7 qtrssince 2023-Q1
Increased
57

INSMED INC

3.3M$238.9M3.5%$44.25+63.78%
6 qtrssince 2023-Q2
Decreased
0

ACADIA Pharmaceuticals Inc.

13.7M$210.8M3.1%$18.35-14.49%
10 qtrssince 2022-Q2
Unchanged
0
MRUSMRUSDelisted

MERUS N V

4.2M$208.3M3.0%$34.06+40.18%
6 qtrssince 2023-Q2
Unchanged
0

GERON CORP

44.1M$200.3M2.9%$4.57-66.52%
1 qtr
New
79
MASIMASIDelisted

MASIMO CORP

1.5M$195M2.8%$174.28-23.57%
23 qtrssince 2019-Q1
Unchanged
0

ALKERMES PLC

6.7M$186.2M2.7%$27.05+3.47%
5 qtrssince 2023-Q3
Decreased
0
AKROAKRODelisted

AKERO THERAPEUTICS INC

5.9M$169.8M2.5%$24.35+15.99%
4 qtrssince 2023-Q4
Increased
57

APOGEE THERAPEUTICS INC

2.7M$159.3M2.3%$28.34+104.64%
5 qtrssince 2023-Q3
Unchanged
0

PENUMBRA INC

795,750$154.6M2.2%$250.56-23.55%
13 qtrssince 2021-Q3
Increased
56
IMCRIMCR
ADR

IMMUNOCORE HLDGS PLC

4.9M$151.6M2.2%$43.05-27.06%
15 qtrssince 2021-Q1
Unchanged
0
$6.9B
AUM
68
Positions
Q3 2024
Filing
Rating · 3.0
Quarterly Portfolio Change
+9%Q2'23$5.3B-10%Q3'23$4.7B+35%Q4'23$6.4B+6%Q1'24$6.8B-5%Q2'24$6.5B+7%Q3'24$6.9B
Activity profile
$ moved · Q3'24
New40%Increased32%Decreased10%Exited18%
Composition
Equity vs derivatives
Equity100%Puts0%Calls0%
Holding period
Avg 2.4 years
<1Q10%1-4Q26%1-2Y16%2Y+47%

RTW INVESTMENTS, LP manages $6.9B across 68 positions as of Q3 2024. Top holdings: MDGL (6.1%), AXSM (5.4%), RNAM (5.4%). Fund DNA: Balanced Allocator. HoldingsIntel Rating: 3/5.0.

Q3 2024 Summary

Active quarter - 11 new positions, 11 exits, 14 increased. Top move: GERN (NEW, conviction 79). Portfolio: $6.9B across 68 positions.

Top holdings by portfolio weight

Total AUM$7B
MDGL6.12%
AXSM5.45%
RNAM5.40%
ARGX5.13%
NTRA4.76%
RCKT4.73%
PTCT3.97%
DYN3.54%
PTGX3.53%
BRKR3.48%
Other3.46%

Portfolio allocation by GICS sector

Sectors3
Healthcare94.33%
Unknown5.56%
Financial Services0.11%

Behavioral investing profile

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Balanced Allocator- primarily Healthcare
Compare DNA across all funds
7-dimension quality assessment
Solid(3.0 / 5.0)
Track Record36
Conviction45
Concentration72
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Position Outcomes

Best and worst performing positions by estimated return

Cost basis estimates based on full filing history using quarter-end prices. Actual transaction prices are not disclosed in 13F filings.

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Data sourced from SEC EDGAR 13F filings. Not financial advice. Full disclaimer

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